RT Journal Article SR Electronic(1) A1 Palese, P. A1 Compans, R. W.YR 1976 T1 Inhibition of Influenza Virus Replication in Tissue Culture by 2-deoxy-2,3-dehydro-N-trifluoroacetylneuraminic acid (FANA): Mechanism of Action JF Journal of General Virology, VO 33 IS 1 SP 159 OP 163 DO https://doi.org/10.1099/0022-1317-33-1-159 PB Microbiology Society, SN 1465-2099, AB SUMMARY The neuraminidase inhibitor 2-deoxy-2,3-dehydro-N-trifluoroacetylneuraminic acid (FANA) inhibits the multicycle replication of influenza viruses in tissue culture. Influenza virus grown in the presence of FANA contains neuraminic acid on its envelope which then serves as receptor for other virus particles causing extensive aggregation. Thus, FANA inhibits influenza virus replication by preventing the enzymatic removal of neuraminic acid from the virus envelope., UL https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-33-1-159