Cytopathic Effect and Plaque Formation by Arboviruses in a Continuous Cell Line (XTC-2) from the Toad Xenopus laevis Leake, C. J. and Varma, M. G. R. and Pudney, Mary,, 35, 335-339 (1977), doi = https://doi.org/10.1099/0022-1317-35-2-335, publicationName = Microbiology Society, issn = 0022-1317, abstract= SUMMARY Forty-six arboviruses were tested for c.p.e. and/or plaque formation in an amphibian cell line. C.p.e. was observed with a high proportion of the viruses tested. Comparative plaque assay, in the XTC-2 cells at 28 °C and Vero cells at 37 °C, suggests that these systems are comparable in sensitivity and susceptibility to infection. Practical uses of this cell line are discussed., language=, type=