Presence of Genomic Polyadenylate and Absence of Detectable Virion Transcriptase in Human Coronavirus OC-43
Tannock, Gregory A. and Hierholzer, John C.,, 39, 29-39 (1978),
doi = https://doi.org/10.1099/0022-1317-39-1-29,
publicationName = Microbiology Society,
issn = 0022-1317,
abstract= SUMMARY Human coronavirus RNA, prepared by extraction of purified virions with phenol-chloroform, consists of a major 15 to 55S class and a minor 4S class of RNA fragments. Polyadenylic acid [poly (A)] sequences are present in 15 to 55S but not in 4S RNA, suggesting different functions for each class. A stretch of poly (A) of approximately 19 adenosine monophosphate residues was obtained in sizing experiments after digesting OC-43 RNA with pancreatic and T1 ribonucleases. An OC-43 virion RNA transcriptase could not be detected with systems optimal for detecting the transcriptases of influenza and Newcastle disease virus.,
language=,
type=