f The Effect of Δ-9-Tetrahydrocannabinol on Herpes Simplex Virus Replication
- Authors: R. Dean Blevins, Michael P. Dumic
- J. Gen. Virol., August 1980 49: 427-431, doi: 10.1099/0022-1317-49-2-427
- Subject: Animal
- Published Online:
Both herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2) failed, in an identical fashion to replicate and produce extensive c.p.e. in human cell monolayer cultures which were exposed (8 h before infection, at infection, or 8 h p.i.) to various concentrations of Δ-9-tetrahydrocannabinol. Similar results were obtained with a plaque assay utilizing confluent monkey cells. Possible mechanisms for this antiviral activity are discussed.
© Society for General Microbiology 1980 | Published by the Microbiology Society
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