@article{mbs:/content/journal/jgv/10.1099/0022-1317-49-2-427, author = "Blevins, R. Dean and Dumic, Michael P.", title = "The Effect of Δ-9-Tetrahydrocannabinol on Herpes Simplex Virus Replication", journal= "Journal of General Virology", year = "1980", volume = "49", number = "2", pages = "427-431", doi = "https://doi.org/10.1099/0022-1317-49-2-427", url = "https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-49-2-427", publisher = "Microbiology Society", issn = "1465-2099", type = "Journal Article", abstract = "SUMMARY Both herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2) failed, in an identical fashion to replicate and produce extensive c.p.e. in human cell monolayer cultures which were exposed (8 h before infection, at infection, or 8 h p.i.) to various concentrations of Δ-9-tetrahydrocannabinol. Similar results were obtained with a plaque assay utilizing confluent monkey cells. Possible mechanisms for this antiviral activity are discussed.", }