1887

Abstract

SUMMARY

The antigenic specificity of antibody-dependent plaque enhancement (ADPE) on the macrophage cell line P388D1 has been investigated using viruses in the flavivirus and alphavirus genera. Whereas ADPE detected group-specific antigenic determinants in the flaviviruses, narrower specificity (type and subgroup) was seen with alphaviruses. ADPE titres correlated well with haemagglutination inhibition titres.

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/content/journal/jgv/10.1099/0022-1317-58-2-291
1982-02-01
2024-04-25
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