%0 Journal Article %A Walsh, Edward E. %A Schlesinger, Jacob J. %A Brandriss, Michael W. %T Purification and Characterization of GP90, One of the Envelope Glycoproteins of Respiratory Syncytial Virus %D 1984 %J Journal of General Virology, %V 65 %N 4 %P 761-767 %@ 1465-2099 %R https://doi.org/10.1099/0022-1317-65-4-761 %K RSV %K glycoprotein %K purification %I Microbiology Society, %X SUMMARY The large glycoprotein, GP90, of respiratory syncytial virus (RSV) was purified by affinity chromatography using a monoclonal antibody. Hyperimmune rabbit antiserum directed specifically to the purified GP90 neutralized RSV to high titre but did not inhibit fusion of previously infected cells. 125I-labelled GP90 bound rapidly to HEp-2 cells in an unsaturable manner; binding was inhibited by the hyperimmune rabbit antiserum. %U https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-65-4-761