Determination of the Sequence Alteration in the DNA of the Herpes Simplex Virus Type 1 Temperature-sensitive Mutant ts K
Davison, M.-J. and Preston, V. G. and McGeoch, D. J.,, 65, 859-863 (1984),
doi = https://doi.org/10.1099/0022-1317-65-5-859,
publicationName = Microbiology Society,
issn = 0022-1317,
abstract= SUMMARY The alteration in the DNA sequence responsible for the mutant phenotype of the herpes simplex virus type 1 temperature-sensitive mutant ts K has been determined. A single C:G base pair present in the wild-type Vmw 175 immediate-early polypeptide-coding sequence has been replaced by T:A in the mutant gene. This results in the substitution of an alanine by a valine codon. In two revertants the mutant T:A base pair has been resubstituted by C:G.,
language=,
type=