1887

Abstract

SUMMARY

LeDantec virus, originally recovered in 1965 from a patient with a febrile illness in Senegal, was observed by thin section electron microscopy to be bullet-shaped, representative of members of the rhabdovirus group, with mean dimensions of 164 × 78 nm. Particles were observed budding from the plasma membrane and moderate numbers accumulated in the intercellular spaces. In three mammalian cell lines, LeDantec virus was rapidly cytopathic and replicated to moderately high titres. In complement fixation tests with other known rhabdoviruses, LeDantec was found to be related to Keuraliba virus, a previously ungrouped agent isolated from rodents in Senegal in 1968. We propose the formation of a new LeDantec serogroup comprising these two viruses.

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1985-12-01
2024-04-24
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References

  1. Berge T. O. 1975 International Catalogue of Arboviruses Including Certain Other Viruses of Vertebrates DHEW Publication No. (CDC) 75–8301 U.S. Department of Health; Education and Welfare:
    [Google Scholar]
  2. Casey H. L. 1965; Standardized diagnostic complement-fixation method and adaptation to micro test. II. Adaptation of LBCF method to micro technique. In Public Health Service Monograph No 74: pp 31–34 Washington, D.C:
    [Google Scholar]
  3. Clarke D. H., Casals J. 1958; Techniques for hemagglutination and hemagglutination-inhibition with arthropod-borne viruses. American Journal of Tropical Medicine and Hygiene 7:561–573
    [Google Scholar]
  4. Haschemeyer R. H., Myers R. S. 1972; Negative staining. In Principles and Techniques of Electron Microscopy: Biological Application 2: pp 101–122 Edited by Hayst M. A. New York: Van Nostrand Reinhold;
    [Google Scholar]
  5. Monath T. P., CROPP C. B., Frazer C. L., Murphy F. A., Whitfield S. A. 1979; Viruses isolated from reptiles: identification of three new members of the family Rhabdoviridae. Archives of Virology 60:1–12
    [Google Scholar]
  6. Murphy F. A., Harrison A. K. 1979; Electron microscopy of the rhabdoviruses of animals. In Rhabdoviruses vol 1:66–78 Edited by Bishop D. H. L. Boca Raton: CRC Press;
    [Google Scholar]
  7. Reed L. J., Muench H. 1938; A simple method of estimating fifty percent end points. American Journal of Hygiene 27:493–497
    [Google Scholar]
  8. Tesh R. B., Saidi S., Javadian E., Loh P., Nadian A. 1977; Isfahan virus, a new vesiculovirus infecting humans, gerbils and sandflies in Iran. American Journal of Tropical Medicine and Hygiene 26:299–306
    [Google Scholar]
  9. Tesh R. B., Travassos da rosa A. P. A., Travassos da Rosa J. S. 1983; Antigenic relationship among rhabdoviruses infecting terrestrial vertebrates. Journal of General Virology 64:169–176
    [Google Scholar]
  10. Venable J. H., Coggeshall R. 1965; A simplified lead citrate stain for use in electron microscopy. Journal of Cell Biology 25:407–408
    [Google Scholar]
  11. Woodruff A. W., Ansdell V. E., Bowen E. T. W. 1977; LeDantec virus infection in a patient who had not been in West Africa. British Medical Journal 24–31; 1631–1633
    [Google Scholar]
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