@article{mbs:/content/journal/jgv/10.1099/0022-1317-67-12-2803, author = "James, W. S. and Millican, D.", title = "Host-adaptive Antigenic Variation in Bunyaviruses", journal= "Journal of General Virology", year = "1986", volume = "67", number = "12", pages = "2803-2806", doi = "https://doi.org/10.1099/0022-1317-67-12-2803", url = "https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-67-12-2803", publisher = "Microbiology Society", issn = "1465-2099", type = "Journal Article", keywords = "Bunyamwera virus", keywords = "host-adaptive antigenicity", keywords = "neutralization", keywords = "snowshoe hare virus", abstract = "Summary Bunyamwera virus and snowshoe hare virus (family Bunyaviridae) were passaged up to six times through mosquito cells in culture and the resultant viruses were compared to the input, mammalian cell-passed virus using monoclonal antibodies raised against the input virus. The mosquito cell-adapted virus population consisted of mutants which were better adapted to replication in the new host than was the input mammalian cell-passed virus and were differentially susceptible to neutralization by antibody.", }