%0 Journal Article %A Graham, A. %A Kudesia, G. %A Allen, A. M. %A Desselberger, U. %T Reassortment of Human Rotavirus Possessing Genome Rearrangements with Bovine Rotavirus: Evidence for Host Cell Selection %D 1987 %J Journal of General Virology, %V 68 %N 1 %P 115-122 %@ 1465-2099 %R https://doi.org/10.1099/0022-1317-68-1-115 %I Microbiology Society, %X SUMMARY Mixed infections of secondary rhesus monkey kidney cells with human rotaviruses carrying rearranged genomes and with bovine rotavirus yielded a high percentage of reassortants. The genotypes of 511 plaque-purified clones raised in either MA104 or BSC-1 cells have been determined and the frequencies of different genotypes have been calculated. It was found that (i) reassortants did not emerge at random; (ii) there was non-random association of certain genes; (iii) the cell line used to isolate reassortants influenced the result, i.e. host cell factors had a selective effect on a recombinational mixture. %U https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-68-1-115