RT Journal Article SR Electronic(1) A1 Johnson, Philip R. A1 Collins, Peter L.YR 1988 T1 The Fusion Glycoproteins of Human Respiratory Syncytial Virus of Subgroups A and B: Sequence Conservation Provides a Structural Basis for Antigenic Relatedness JF Journal of General Virology, VO 69 IS 10 SP 2623 OP 2628 DO https://doi.org/10.1099/0022-1317-69-10-2623 PB Microbiology Society, SN 1465-2099, AB Summary Two major antigenic subgroups (A and B) have been described for human respiratory syncytial virus. The complete nucleotide sequence was determined for the fusion (F) mRNA of the subgroup B strain 18537 and the amino acid sequence of the F protein deduced, for comparison with the previously described sequences for the A2 strain of subgroup A. The F proteins (excluding the cleaved signal peptide) were 91% identical between the subgroups, consistent with the previously described high degree of antigenic relatedness. The greatest divergence occurred within the F2 subunit immediately preceding the cleavage activation site., UL https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-69-10-2623