The Large Viral RNA Segment of California Serogroup Bunyaviruses Encodes the Large Viral Protein
Endres, Michael J. and Jacoby, *David R. and Janssen, Robert S. and Gonzalez-Scarano, Francisco and Nathanson, Neal,, 70, 223-228 (1989),
doi = https://doi.org/10.1099/0022-1317-70-1-223,
publicationName = Microbiology Society,
issn = 0022-1317,
abstract= SUMMARY Reassortant bunyaviruses derived from two members of the California serogroup (La Crosse/original and Tahyna/181-57) viruses were used to demonstrate that the large M r viral protein (L) is encoded by the L RNA segment. Radiolabelled viral proteins were analysed by discontinuous SDS–PAGE. The L protein of La Crosse virus was observed to migrate ahead of its Tahyna virus counterpart when electrophoresed through a 5% acrylamide resolving gel. Among the reassortant viruses, the L protein phenotype segregated with the viral L RNA segment. After confirming the genotype of the viruses used in this study, it was concluded that the L RNA species of California serogroup viruses codes for the L protein, the presumed viral polymerase.,
language=,
type=