1887

Abstract

Amino-terminal amino acid sequencing was carried out on proteins purified from herpes simplex virus type 1 capsids. The sequences of two capsid proteins (VP19C and VP23) showed them to be encoded by genes UL38 and UL18, respectively. The product of UL38 has been shown to be essential for capsid assembly, but no role has previously been assigned to the product of UL18.

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1990-05-01
2024-04-18
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References

  1. Baer R., Bankier A. T., Biggin M. D., Deininger P. L., Farrell P. J., Gibson T. J., Hatfull G., Hudson G. S., Satchwell S. C., Séguin C., Tuffnell P. S., Barrell B. G. 1984; DNA sequence and expression of the B95-8 Epstein-Barr virus genome. Nature; London: 310207–211
    [Google Scholar]
  2. Braun D. K., Batterson W., Roizman B. 1984a; Identification and genetic mapping of a herpes simplex virus capsid protein that binds DNA. Journal of Virology 50:645–648
    [Google Scholar]
  3. Braun D. K., Roizman B., Pereira L. 1984b; Characterization of posttranslational products of herpes simplex virus gene 35 proteins binding to the surface of full but not empty capsids. Journal of Virology 49:142–153
    [Google Scholar]
  4. Cohen G. H., Ponce De Leon M., Diggelmann H., Lawrence W. C., Vernon S. K., Eisenberg R. J. 1980; Structural analysis of the capsid polypeptides of herpes simplex virus types 1 and 2. Journal of Virology 34:521–531
    [Google Scholar]
  5. Costa R. H., Cohen G., Eisenberg R., Long D., Wagner E. 1984; Direct demonstration that the abundant 6-kilobase herpes simplex virus type 1 mRNA mapping between 0-23 and 0-27 map units encodes the major capsid protein VP5. Journal of Virology 49:287–292
    [Google Scholar]
  6. Dargan D. J. 1986; The structure and assembly of herpesviruses. In Electron Microscopy of Proteins 5 Virus Structure pp 359–437 Harris J. R., Horne R. W. Edited by London: Academic Press;
    [Google Scholar]
  7. Davison A. J., Scott J. E. 1986a; DNA sequence of the major capsid protein gene of herpes simplex virus type 1. Journal of General Virology 67:2279–2286
    [Google Scholar]
  8. Davison A. J., Scott J. E. 1986b; The complete DNA sequence of varicella-zoster virus. Journal of General Virology 67:1759–1816
    [Google Scholar]
  9. Fling S. P., Gregerson D. S. 1986; Peptide and protein molecular weight determination by electrophoresis using a high molarity Tris buffer system without urea. Analytical Biochemistry 155:83–88
    [Google Scholar]
  10. Gibson W., Roizman B. 1972; Proteins specified by herpes simplex virus. VIII. Characterization and composition of multiple capsid forms of subtypes 1 and 2. Journal of Virology 10:1044–1052
    [Google Scholar]
  11. Heilman C. J.Jr Zweig M., Stephenson J. R., Hampar B. 1979; Isolation of nucleocapsid polypeptides of herpes simplex types 1 and 2 possessing immunologically type-specific and crossreactive determinants. Journal of Virology 29:34–42
    [Google Scholar]
  12. Heine J. W., Honess R. W., Cassai E., Roizman B. 1974; Proteins specified by herpes simplex virus. XII. The virion polypeptides of type 1 strains. Journal of Virology 14:640–651
    [Google Scholar]
  13. Irmiere A., Gibson W. 1985; Isolation of human cytomegalovirus intranuclear capsids, characterization of their protein constituents, and demonstration that the B-capsid assembly protein is also abundant in noninfectious enveloped particles. Journal of Virology 56:277–283
    [Google Scholar]
  14. Lemaster S., Roizman B. 1980; Herpes simplex virus phospho- proteins. II. Characterization of the virion protein kinase and of the polypeptides phosphorylated in the virion. Journal of Virology 35:798–811
    [Google Scholar]
  15. McGeoch D. J., Dolan A., Donald S., Rixon F. J. 1985; Sequence determination and genetic content of the short unique region in the genome of herpes simplex virus type 1. Journal of Molecular Biology 181:1–13
    [Google Scholar]
  16. McGeoch D. J., Dolan A., Donald S., Brauer D. H. K. 1986; Complete DNA sequence of the short repeat region in the genome of herpes simplex virus type 1. Nucleic Acids Research 14:1727–1745
    [Google Scholar]
  17. McGeoch D. J., Dalrymple M. A., Davison A. J., Dolan A., Frame M. C., Mcnab D., Perry L. J., Scott J. E., Taylor P. 1988; The complete DNA sequence of the long unique region in the genome of herpes simplex type 1. Journal of General Virology 69:1531–1574
    [Google Scholar]
  18. Matsudaira P. 1987; Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes. Journal of Biological Chemistry 262:10035–10038
    [Google Scholar]
  19. Perry L. J., McGeoch D. J. 1988; The DNA sequences of the long repeat region and adjoining parts of the long unique region in the genome of herpes simplex virus type 1. Journal of General Virology 69:2831–2846
    [Google Scholar]
  20. Pertuiset B., Boccara M., Cebrian J., Berthelot N., Chouster-Man S., Puvion-Dutilleul F., Sisman J., Sheldrick P. 1989; Physical mapping and nucleotide sequence of a herpes simplex virus type 1 gene required for capsid assembly. Journal of Virology 63:2169–2179
    [Google Scholar]
  21. Preston V. G., Coates J. A. V., Rixon F. J. 1983; Identification and characterization of a herpes simplex virus gene product required for encapsidation of virus DNA. Journal of Virology 45:1056–1064
    [Google Scholar]
  22. Schrag J. D., Venkataram Prasad B. V., Rixon F. J., Chiu W. 1989; Three-dimensional structure of the HSV1 nucleocapsid. Cell 56:651–660
    [Google Scholar]
  23. Vernon S. K., Ponce De Leon M., Cohen G. H., Eisenberg R. J., Rubin B. A. 1981; Morphological components of herpesvirus. III. Localization of herpes simplex virus type 1 nucleocapsid polypeptides by immune electron microscopy. Journal of General Virology 54:39–46
    [Google Scholar]
  24. Weller S. K., Carmichael E. P., Aschman D. P., Goldstein D. J., Schaffer P. A. 1987; Genetic and phenotypic characterization of mutants in four essential genes that map to the left half of HSV-1 U LDNA. Virology 161:198–210
    [Google Scholar]
  25. Zweig M., Heilman C. J., Hampar B. 1979; Identification of disulfide-linked protein complexes in the nucleocapsids of herpes simplex type 2. Virology 94:442–450
    [Google Scholar]
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