f Non-random reassortment between the tripartite RNA genomes of La Crosse and snowshoe hare viruses
- Authors: Virginia Urquidi, David H. L. Bishop
- First Published Online: 01 September 1992, Journal of General Virology 73: 2255-2265, doi: 10.1099/0022-1317-73-9-2255
- Subject: Animal
- Published Online:
The process of reassortment between the tripartite RNA genomes (segments designated L, M and S) of snowshoe hare and La Crosse bunyaviruses (Bunyaviridae) has been investigated by polymerase chain reaction analysis of > 250 progeny recovered at 72 h post-infection from dual wild-type virus infections involving high multiplicities (approximately 5) of each virus in a BHK-21 cell line. Statistical analysis of the data indicated that RNA segment reassortment was not random, and for these two viruses the data appeared to fit the hypothesis that there was a preference for homologous L-M and M-S associations among the progeny formed.
© Society for General Microbiology 1992 | Published by the Microbiology Society
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