Entire nucleotide sequence and characterization of a hepatitis C virus of genotype V/3a
Sakamoto, Minoru and Akahane, Yoshihiro and Tsuda, Fumio and Tanaka, Takeshi and Woodfield, D. Graeme and Okamoto, Hiroaki,, 75, 1761-1768 (1994),
doi = https://doi.org/10.1099/0022-1317-75-7-1761,
publicationName = Microbiology Society,
issn = 0022-1317,
abstract= The entire nucleotide sequence of a hepatitis C virus (HCV) genome (NZL1) of genotype V/3a was determined from overlapping cDNA clones obtained from a human carrier in New Zealand. It comprised 9425 nucleotides (nt) including a 5-untranslated region of 339 nt, a single large open reading frame encoding a polyprotein of 3021 amino acids, a 3′-untranslated region of 23 nt, and 3 -terminal poly(U) stretches of variable lengths. The NZL1 genome was compared with 15 HCV isolates of other genotypes for which the full- length sequence has been determined. It differed from them by 31·1 to 34·3% in nucleotide sequence identity and by 24·5 to 29·1% in amino acid sequence identity, confirming the distinction of genotype V/3a from the other isolates. The nucleotide sequence data reported in this paper are deposited in the DDBJ/GenBank/EMBL Data Libraries under the accession no. D17763.,
language=,
type=