The complete sequence of a human astrovirus
Willcocks, M. M. and Brown, T. D. K. and Madeley, C. R. and Carter, M. J.,, 75, 1785-1788 (1994),
doi = https://doi.org/10.1099/0022-1317-75-7-1785,
publicationName = Microbiology Society,
issn = 0022-1317,
abstract= We have determined the complete genomic sequence of human astrovirus serotype 1 isolated in Newcastle upon Tyne. The genome is 6813 nucleotides long and contains three sequential open reading frames (ORFs). The two closest to the 5′ end are linked by a ribosomal frameshifting motif and contain sequence motifs indicative of non-structural virus proteins: serine protease and RNA-dependent RNA polymerase. A nuclear addressing sequence is also located here. The 3′ ORF encodes the virion structural polypeptides as a polyprotein precursor. This genomic organization resembles that of the plant virus family Luteoviridae. Nucleotide sequence data described in this paper appear in the EMBL database under accession no. Z25771.,
language=,
type=