RT Journal Article SR Electronic(1) A1 Filippone, Claudia A1 Castel, Guillaume A1 Murri, Séverine A1 Beaulieux, Frédérik A1 Ermonval, Myriam A1 Jallet, Corinne A1 Wise, Emma L. A1 Ellis, Richard J. A1 Marston, Denise A. A1 McElhinney, Lorraine M. A1 Fooks, Anthony R. A1 Desvars, Amélie A1 Halos, Lénaı¨g A1 Vourc'h, Gwenaël A1 Marianneau, Philippe A1 Tordo, NoëlYR 2016 T1 Discovery of hantavirus circulating among Rattus rattus in French Mayotte island, Indian Ocean JF Journal of General Virology, VO 97 IS 5 SP 1060 OP 1065 DO https://doi.org/10.1099/jgv.0.000440 PB Microbiology Society, SN 1465-2099, AB Hantaviruses are emerging zoonotic viruses that cause human diseases. In this study, sera from 642 mammals from La Réunion and Mayotte islands (Indian Ocean) were screened for the presence of hantaviruses by molecular analysis. None of the mammals from La Réunion island was positive, but hantavirus genomic RNA was discovered in 29/160 (18 %) Rattus rattus from Mayotte island. The nucleoprotein coding region was sequenced from the liver and spleen of all positive individuals allowing epidemiological and intra-strain variability analyses. Phylogenetic analysis based on complete coding genomic sequences showed that this Murinae-associated hantavirus is a new variant of Thailand virus. Further studies are needed to investigate hantaviruses in rodent hosts and in Haemorrhagic Fever with Renal Syndrome (HFRS) human cases., UL https://www.microbiologyresearch.org/content/journal/jgv/10.1099/jgv.0.000440