HPV-11 variability, persistence and progression to genital warts in men: the HIM study
Flores-Díaz, Ema and Sereday, Karen A. and Ferreira, Silvaneide and Sirak, Bradley and Sobrinho, João Simão and Baggio, Maria Luiza and Galan, Lenice and Silva, Roberto C. and Lazcano-Ponce, Eduardo and Giuliano, Anna R. and Villa, Luisa L. and Sichero, Laura and the HIM Study Group,, 98, 2339-2342 (2017),
doi = https://doi.org/10.1099/jgv.0.000896,
publicationName = Microbiology Society,
issn = 0022-1317,
abstract= HPV-11 and HPV-6 are the etiological agents of about 90 % of genital warts (GWs). The intra-typic variability of HPV-11 and its association with infection persistence and GW development remains undetermined. Here, HPV infection in men (HIM) participants who had an HPV-11 genital swab and/or GW, preceded or not by a normal skin genital swab were analysed. Genomic variants were characterized by PCR-sequencing and classified within lineages (A, B) and sublineages (A1, A2, A3, A4). HPV-11 A2 variants were the most frequently detected in the genital swab samples from controls and in both genital swabs and GW samples from cases. The same HPV-11 variant was detected in the GW sample and its preceding genital swab. There was a lack of association between any particular HPV-11 variant and the increased risk for GW development.,
language=,
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