%0 Journal Article %A Purdy, Michael A. %A Harrison, Tim J. %A Jameel, S. %A Meng, X-J. %A Okamoto, H. %A Van der Poel, W. H. M. %A Smith, Donald B. %A ICTV Report Consortium %T ICTV Virus Taxonomy Profile: Hepeviridae %D 2017 %J Journal of General Virology, %V 98 %N 11 %P 2645-2646 %@ 1465-2099 %R https://doi.org/10.1099/jgv.0.000940 %K piscihepevirus %K avian hepatitis E virus %K hepatitis E virus %K swine hepatitis E virus %K Hepeviridae %K taxonomy %K ICTV %I Microbiology Society, %X The family Hepeviridae includes enterically transmitted small non-enveloped positive-sense RNA viruses. It includes the genera Piscihepevirus, whose members infect fish, and Orthohepevirus, whose members infect mammals and birds. Members of the genus Orthohepevirus include hepatitis E virus, which is responsible for self-limiting acute hepatitis in humans and several mammalian species; the infection may become chronic in immunocompromised individuals. Extrahepatic manifestations of Guillain–Barré syndrome, neuralgic amyotrophy, glomerulonephritis and pancreatitis have been described in humans. Avian hepatitis E virus causes hepatitis–splenomegaly syndrome in chickens. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the taxonomy of the Hepeviridae, which is available at www.ictv.global/report/hepeviridae. %U https://www.microbiologyresearch.org/content/journal/jgv/10.1099/jgv.0.000940