RT Journal Article SR Electronic(1) A1 Purdy, Michael A. A1 Harrison, Tim J. A1 Jameel, S. A1 Meng, X-J. A1 Okamoto, H. A1 Van der Poel, W. H. M. A1 Smith, Donald B. A1 ICTV Report ConsortiumYR 2017 T1 ICTV Virus Taxonomy Profile: Hepeviridae JF Journal of General Virology, VO 98 IS 11 SP 2645 OP 2646 DO https://doi.org/10.1099/jgv.0.000940 PB Microbiology Society, SN 1465-2099, AB The family Hepeviridae includes enterically transmitted small non-enveloped positive-sense RNA viruses. It includes the genera Piscihepevirus, whose members infect fish, and Orthohepevirus, whose members infect mammals and birds. Members of the genus Orthohepevirus include hepatitis E virus, which is responsible for self-limiting acute hepatitis in humans and several mammalian species; the infection may become chronic in immunocompromised individuals. Extrahepatic manifestations of Guillain–Barré syndrome, neuralgic amyotrophy, glomerulonephritis and pancreatitis have been described in humans. Avian hepatitis E virus causes hepatitis–splenomegaly syndrome in chickens. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the taxonomy of the Hepeviridae, which is available at www.ictv.global/report/hepeviridae. , UL https://www.microbiologyresearch.org/content/journal/jgv/10.1099/jgv.0.000940