1887

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Volume 99, Issue 2

mosquitoes do not support replication of Zika virus Open Access

Abstract

The rapid spread of Zika virus (ZIKV) in the Americas raised many questions about the role of mosquitoes in transmission, in addition to the key role played by the vector . Here we analysed the competence of (with or without endosymbionts) for a ZIKV isolate. We also examined the induction of RNA interference pathways after viral challenge and the production of small virus-derived RNAs. We did not observe any infection nor such small virus-derived RNAs, regardless of the presence or absence of . Thus, does not support ZIKV replication and is not involved in producing this phenotype. In short, these mosquitoes are very unlikely to play a role in transmission of ZIKV.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): Culex spp. mosquitoes , mosquito , replication , transmission and Zika virus
© 2018 The Authors
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2018-02-01
2024-04-24
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Culex quinquefasciatus mosquitoes do not support replication of Zika virus
J. Gen. Virol. 99, 258 (2018); https://doi.org/10.1099/jgv.0.000949
/content/journal/jgv/10.1099/jgv.0.000949
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