Molecular characterization of Porcine sapelovirus in Hunan, China
Yang, Taotao and Yu, Xinglong and Yan, Meijun and Luo, Binyu and Li, Runcheng and Qu, Tailong and Luo, Zhang and Ge, Meng and Zhao, Dun,, 98, 2738-2747 (2017),
doi = https://doi.org/10.1099/jgv.0.000951,
publicationName = Microbiology Society,
issn = 0022-1317,
abstract= Porcine sapeloviruses (PSVs) are widely distributed in pig populations; however, little information on their evolutionary history and the mechanisms driving their divergence is available. Therefore, in the present study, 241 fecal samples and 91 intestinal contents collected from pigs at 26 farms in Hunan, China, were tested for the presence of PSVs. The overall PSV positivity rate was 46.39 %, with a particularly high infection rate detected in nursery and fattening pigs. A total of 29 PSV strains (PSV-HuNs) were isolated, with these showing high genetic diversity based on phylogenetic and pairwise distance analyses of the capsid-protein gene sequences. Incongruence between phylognetic trees of the capsid-protein and 3CD regions indicated frequent recombination within the PSV-HuNs, and a putative recombinant hotspot near the 3′ end of the P1 region was identified. Our results suggested that recombination played an important role in driving PSV genetic diversity and evolution.,
language=,
type=