Fish polyomaviruses belong to two distinct evolutionary lineages
Van Doorslaer, Koenraad and Kraberger, Simona and Austin, Charlotte and Farkas, Kata and Bergeman, Melissa and Paunil, Emma and Davison, William and Varsani, Arvind,, 99, 567-573 (2018),
doi = https://doi.org/10.1099/jgv.0.001041,
publicationName = Microbiology Society,
issn = 0022-1317,
abstract= The Polyomaviridae is a diverse family of circular double-stranded DNA viruses. Polyomaviruses have been isolated from a wide array of animal hosts. An understanding of the evolutionary and ecological dynamics of these viruses is essential to understanding the pathogenicity of polyomaviruses. Using a high throughput sequencing approach, we identified a novel polyomavirus in an emerald notothen (Trematomus bernacchii) sampled in the Ross sea (Antarctica), expanding the known number of fish-associated polyomaviruses. Our analysis suggests that polyomaviruses belong to three main evolutionary clades; the first clade is made up of all recognized terrestrial polyomaviruses. The fish-associated polyomaviruses are not monophyletic, and belong to two divergent evolutionary lineages. The fish viruses provide evidence that the evolution of the key viral large T protein involves gain and loss of distinct domains.,
language=,
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