1887

Abstract

Several novel astroviruses have been recently discovered in humans and in other animals. Here, we report results from our surveillance of astroviruses in human and rodent faecal samples in Hong Kong. Classical human astroviruses (=9) and a human MLB1 astrovirus were detected in human faecal samples (=622). Novel astroviruses were detected from 1.6 % of the faecal samples of urban brown rat () (=441), indicating the prevalence of astrovirus infection in rats might be much lower than that recently observed in bats. These rat astroviruses were phylogenetically related to recently discovered human astroviruses MLB1 and MLB2, suggesting that the MLB viruses and these novel rat astroviruses may share a common ancestor.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/vir.0.022764-0
2010-10-01
2024-03-28
Loading full text...

Full text loading...

/deliver/fulltext/jgv/91/10/2457.html?itemId=/content/journal/jgv/10.1099/vir.0.022764-0&mimeType=html&fmt=ahah

References

  1. Atkins, A., Wellehan, J. F., Jr, Childress, A. L., Archer, L. L., Fraser, W. A. & Citino, S. B.(2009). Characterization of an outbreak of astroviral diarrhea in a group of cheetahs (Acinonyx jubatus). Vet Microbiol 136, 160–165.[CrossRef] [Google Scholar]
  2. Chu, D. K., Peiris, J. S., Chen, H., Guan, Y. & Poon, L. L.(2008a). Genomic characterizations of bat coronaviruses (1A, 1B and HKU8) and evidence for co-infections in Miniopterus bats. J Gen Virol 89, 1282–1287.[CrossRef] [Google Scholar]
  3. Chu, D. K., Poon, L. L., Guan, Y. & Peiris, J. S.(2008b). Novel astroviruses in insectivorous bats. J Virol 82, 9107–9114.[CrossRef] [Google Scholar]
  4. Drummond, A. J. & Rambaut, A.(2007).beast: Bayesian evolutionary analysis by sampling trees. BMC Evol Biol 7, 214.[CrossRef] [Google Scholar]
  5. Finkbeiner, S. R., Allred, A. F., Tarr, P. I., Klein, E. J., Kirkwood, C. D. & Wang, D.(2008a). Metagenomic analysis of human diarrhea: viral detection and discovery. PLoS Pathog 4, e1000011.[CrossRef] [Google Scholar]
  6. Finkbeiner, S. R., Kirkwood, C. D. & Wang, D.(2008b). Complete genome sequence of a highly divergent astrovirus isolated from a child with acute diarrhea. Virol J 5, 117.[CrossRef] [Google Scholar]
  7. Finkbeiner, S. R., Holtz, L. R., Jiang, Y., Rajendran, P., Franz, C. J., Zhao, G., Kang, G. & Wang, D.(2009a). Human stool contains a previously unrecognized diversity of novel astroviruses. Virol J 6, 161.[CrossRef] [Google Scholar]
  8. Finkbeiner, S. R., Le, B. M., Holtz, L. R., Storch, G. A. & Wang, D.(2009b). Detection of newly described astrovirus MLB1 in stool samples from children. Emerg Infect Dis 15, 441–444.[CrossRef] [Google Scholar]
  9. Finkbeiner, S. R., Ruone, Y. L. S., Conrardy, C., Gregoricu, N., Toney, D., Virgin, H. W., Anderson, L. J., Vinje, J., Wang, D. & Tong, S.(2009c). Identification of a novel astrovirus (astrovirus VA1) associated with an outbreak of acute gastroenteritis. J Virol 83, 10836–10839.[CrossRef] [Google Scholar]
  10. Kapoor, A., Li, L., Victoria, J., Oderinde, B., Mason, C., Pandey, P., Zaidi, S. Z. & Delwart, E.(2009). Multiple novel astrovirus species in human stool. J Gen Virol 90, 2965–2972.[CrossRef] [Google Scholar]
  11. Lole, K. S., Bollinger, R. C., Paranjape, R. S., Gadkari, D., Kulkarni, S. S., Novak, N. G., Ingersoll, R., Sheppard, H. W. & Ray, S. C.(1999). Full-length human immunodeficiency virus type 1 genomes from subtype C-infected seroconverters in India, with evidence of intersubtype recombination. J Virol 73, 152–160. [Google Scholar]
  12. Martin, D. P., Williamson, C. & Posada, D.(2005). RDP2: recombination detection and analysis from sequence alignments. Bioinformatics 21, 260–262.[CrossRef] [Google Scholar]
  13. Mendez, E. & Arias, C. F.(2007). Astroviruses. In Fields Virology, 5th edn, pp. 981–1000. Edited by Howley, P. M., Knipe, D. M., Griffin, D. E., Lamb, R. A., Martin, M. A., Roizman, B. & Straus, S. E.. Philadelphia, PA. : Lippincott Williams & Wilkins. [Google Scholar]
  14. Morse, S. S.(1995). Factors in the emergence of infectious diseases. Emerg Infect Dis 1, 7–15.[CrossRef] [Google Scholar]
  15. Pond, S. L. & Frost, S. D.(2005). A genetic algorithm approach to detecting lineage-specific variation in selection pressure. Mol Biol Evol 22, 478–485. [Google Scholar]
  16. Poon, L. L., Chu, D. K., Chan, K. H., Wong, O. K., Ellis, T. M., Leung, Y. H., Lau, S. K., Woo, P. C., Suen, K. Y. & other authors(2005). Identification of a novel coronavirus in bats. J Virol 79, 2001–2009.[CrossRef] [Google Scholar]
  17. Rivera, R., Nollens, H. H., Venn-Watson, S., Gulland, F. M. & Wellehan, J. F., Jr(2010). Characterization of phylogenetically diverse astroviruses of marine mammals. J Gen Virol 91, 166–173.[CrossRef] [Google Scholar]
  18. Sullivan, R.(2003).Rats: Observations on the History and Habitat of the City's Most Unwanted Inhabitants. New York. : Bloomsbury. [Google Scholar]
  19. Zhu, H. C., Chu, D. K., Liu, W., Dong, B. Q., Zhang, S. Y., Zhang, J. X., Li, L. F., Vijaykrishna, D., Smith, G. J. & other authors(2009). Detection of diverse astroviruses from bats in China. J Gen Virol 90, 883–887.[CrossRef] [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/vir.0.022764-0
Loading
/content/journal/jgv/10.1099/vir.0.022764-0
Loading

Data & Media loading...

Supplements

vol. , part 10, pp. 2457 - 2462

Primers used in determining rat astrovirus sequences [PDF](70 KB)



PDF
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error