RT Journal Article SR Electronic(1) A1 Gubala, Aneta A1 Davis, Steven A1 Weir, Richard A1 Melville, Lorna A1 Cowled, Chris A1 Boyle, DavidYR 2011 T1 Tibrogargan and Coastal Plains rhabdoviruses: genomic characterization, evolution of novel genes and seroprevalence in Australian livestock JF Journal of General Virology, VO 92 IS 9 SP 2160 OP 2170 DO https://doi.org/10.1099/vir.0.026120-0 PB Microbiology Society, SN 1465-2099, AB Tibrogargan virus (TIBV) and Coastal Plains virus (CPV) were isolated from cattle in Australia and TIBV has also been isolated from the biting midge Culicoides brevitarsis. Complete genomic sequencing revealed that the viruses share a novel genome structure within the family Rhabdoviridae, each virus containing two additional putative genes between the matrix protein (M) and glycoprotein (G) genes and one between the G and viral RNA polymerase (L) genes. The predicted novel protein products are highly diverged at the sequence level but demonstrate clear conservation of secondary structure elements, suggesting conservation of biological functions. Phylogenetic analyses showed that TIBV and CPV form an independent group within the ‘dimarhabdovirus supergroup’. Although no disease has been observed in association with these viruses, antibodies were detected at high prevalence in cattle and buffalo in northern Australia, indicating the need for disease monitoring and further study of this distinctive group of viruses., UL https://www.microbiologyresearch.org/content/journal/jgv/10.1099/vir.0.026120-0