1887

Abstract

Although G2P[4] rotaviruses are common causes of acute childhood diarrhoea in Africa, to date there are no reports on whole genomic analysis of African G2P[4] strains. In this study, the nearly complete genome sequences of two Kenyan G2P[4] strains, AK26 and D205, detected in 1982 and 1989, respectively, were analysed. Strain D205 exhibited a DS-1-like genotype constellation, whilst strain AK26 appeared to be an intergenogroup reassortant with a Wa-like NSP2 genotype on the DS-1-like genotype constellation. The VP2-4, VP6-7, NSP1, NSP3 and NSP5 genes of strain AK26 and the VP2, VP4, VP7 and NSP1–5 genes of strain D205 were closely related to those of the prototype or other human G2P[4] strains. In contrast, their remaining genes were distantly related, and, except for NSP2 of AK26, appeared to originate from or share a common origin with rotavirus genes of artiodactyl (ruminant and camelid) origin. These observations highlight the complex evolutionary dynamics of African G2P[4] rotaviruses.

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2011-09-01
2024-03-29
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References

  1. Abe M., Ito N., Morikawa S., Takasu M., Murase T., Kawashima T., Kawai Y., Kohara J., Sugiyama M. 2009; Molecular epidemiology of rotaviruses among healthy calves in Japan: isolation of a novel bovine rotavirus bearing new P and G genotypes. Virus Res 144:250–257 [View Article][PubMed]
    [Google Scholar]
  2. Abe M., Ito N., Masatani T., Nakagawa K., Yamaoka S., Kanamaru Y., Suzuki H., Shibano K., Arashi Y., Sugiyama M. 2011; Whole genome characterization of new bovine rotavirus G21P[29] and G24P[33] strains provides evidence for interspecies transmission. J Gen Virol 92:952–960 [View Article][PubMed]
    [Google Scholar]
  3. Bányai K., Martella V., Molnár P., Mihály I., Van Ranst M., Matthijnssens J. 2009; Genetic heterogeneity in human G6P[14] rotavirus strains detected in Hungary suggests independent zoonotic origin. J Infect 59:213–215 [View Article][PubMed]
    [Google Scholar]
  4. Bányai K., Mijatovic-Rustempasic S., Hull J. J., Esona M. D., Freeman M. M., Frace A. M., Bowen M. D., Gentsch J. R. 2011; Sequencing and phylogenetic analysis of the coding region of six common rotavirus strains: evidence for intragenogroup reassortment among co-circulating G1P[8] and G2P[4] strains from the United States. J Med Virol 83:532–539 [View Article][PubMed]
    [Google Scholar]
  5. Chen Y., Wen Y., Liu X., Xiong X., Cao Z., Zhao Q., Yu Y., Yin X., Li C., Fan Y. 2008; Full genomic analysis of human rotavirus strain TB-Chen isolated in China. Virology 375:361–373 [View Article][PubMed]
    [Google Scholar]
  6. Collins P. J., Martella V., Buonavoglia C., O’Shea H. 2010; Identification of a G2-like porcine rotavirus bearing a novel VP4 type, P[32]. Vet Res 41:73 [View Article][PubMed]
    [Google Scholar]
  7. Cunliffe N. A., Kilgore P. E., Bresee J. S., Steele A. D., Luo N., Hart C. A., Glass R. I. 1998; Epidemiology of rotavirus diarrhoea in Africa: a review to assess the need for rotavirus immunization. Bull World Health Organ 76:525–537[PubMed]
    [Google Scholar]
  8. Cunliffe N. A., Gentsch J. R., Kirkwood C. D., Gondwe J. S., Dove W., Nakagomi O., Nakagomi T., Hoshino Y., Bresee J. S. et al. 2000; Molecular and serologic characterization of novel serotype G8 human rotavirus strains detected in Blantyre, Malawi. Virology 274:309–320 [View Article][PubMed]
    [Google Scholar]
  9. De Grazia S., Giammanco G. M., Potgieter C. A., Matthijnssens J., Banyai K., Platia M. A., Colomba C., Martella V. 2010; Unusual assortment of segments in 2 rare human rotavirus genomes. Emerg Infect Dis 16:859–862[PubMed] [CrossRef]
    [Google Scholar]
  10. Esona M. D., Geyer A., Banyai K., Page N., Aminu M., Armah G. E., Hull J., Steele D. A., Glass R. I., Gentsch J. R. 2009a; Novel human rotavirus genotype G5P[7] from child with diarrhea, Cameroon. Emerg Infect Dis 15:83–86 [View Article][PubMed]
    [Google Scholar]
  11. Esona M. D., Geyer A., Page N., Trabelsi A., Fodha I., Aminu M., Agbaya V. A., Tsion B., Kerin T. K. et al. 2009b ). Genomic characterization of human rotavirus G8 strains from the African rotavirus network: relationship to animal rotaviruses. J Med Virol 81:937–951 [View Article][PubMed]
    [Google Scholar]
  12. Esona M. D., Mijatovic-Rustempasic S., Conrardy C., Tong S., Kuzmin I. V., Agwanda B., Breiman R. F., Banyai K., Niezgoda M. et al. 2010; Reassortant group A rotavirus from straw-colored fruit bat (Eidolon helvum). Emerg Infect Dis 16:1844–1852[PubMed] [CrossRef]
    [Google Scholar]
  13. Esona M. D., Banyai K., Foytich K., Freeman M., Mijatovic-Rustempasic S., Hull J., Kerin T., Steele A. D., Armah G. E., Geyer A. 2011; Genomic characterization of human rotavirus G10 strains from the African Rotavirus Network: relationship to animal rotaviruses. Infect Genet Evol 11:237–241 [View Article][PubMed]
    [Google Scholar]
  14. Estes M. K., Kapikian A. Z. 2007; Rotaviruses and their replication. In Fields Virology, 5th edn. pp. 1917–1974 Edited by Fields B. N., Knipe D. M., Howley P. M., Griffin D. E., Lamb R. A., Martin M. A., Roizman B., Straus S. E. Philadelphia, PA: Lippincott, Williams & Wilkins;
    [Google Scholar]
  15. Gatheru Z., Kobayashi N., Adachi N., Chiba S., Muli J., Ogaja P., Nyangao J., Kiplagat E., Tukei P. M. 1993; Characterization of human rotavirus strains causing gastroenteritis in Kenya. Epidemiol Infect 110:419–423 [View Article][PubMed]
    [Google Scholar]
  16. Ghosh S., Alam M. M., Ahmed M. U., Talukdar R. I., Paul S. K., Kobayashi N. 2010a; Complete genome constellation of a caprine group A rotavirus strain reveals common evolution with ruminant and human rotavirus strains. J Gen Virol 91:2367–2373 [View Article][PubMed]
    [Google Scholar]
  17. Ghosh S., Kobayashi N., Nagashima S., Chawla-Sarkar M., Krishnan T., Ganesh B., Naik T. N. 2010b ). Full genomic analysis and possible origin of a porcine G12 rotavirus strain RU172. Virus Genes 40:382–388 [View Article][PubMed]
    [Google Scholar]
  18. Ghosh S., Gatheru Z., Nyangao J., Adachi N., Urushibara N., Kobayashi N. 2011a; Full genomic analysis of a simian SA11-like G3P[2] rotavirus strain isolated from an asymptomatic infant: identification of novel VP1, VP6 and NSP4 genotypes. Infect Genet Evol 11:57–63 [View Article][PubMed]
    [Google Scholar]
  19. Ghosh S., Gatheru Z., Nyangao J., Adachi N., Urushibara N., Kobayashi N. 2011b ). Full genomic analysis of a G8P[1] rotavirus strain isolated from an asymptomatic infant in Kenya provides evidence for an artiodactyl-to-human interspecies transmission event. J Med Virol 83:367–376 [View Article][PubMed]
    [Google Scholar]
  20. Ghosh S., Paul S. K., Hossain M. A., Alam M. M., Ahmed M. U., Kobayashi N. 2011c ). Full genomic analyses of two human G2P[4] rotavirus strains detected in 2005: identification of a caprine-like VP3 gene. J Gen Virol 92:1222–1227 [View Article][PubMed]
    [Google Scholar]
  21. Gorziglia M., Hoshino Y., Nishikawa K., Maloy W. L., Jones R. W., Kapikian A. Z., Chanock R. M. 1988; Comparative sequence analysis of the genomic segment 6 of four rotaviruses each with a different subgroup specificity. J Gen Virol 69:1659–1669 [View Article][PubMed]
    [Google Scholar]
  22. Jere K. C., Sawyerr T., Seheri L. M., Peenze I., Page N. A., Geyer A., Steele A. D. 2011; A first report on the characterization of rotavirus strains in Sierra Leone. J Med Virol 83:540–550 [View Article][PubMed]
    [Google Scholar]
  23. Khoury H., Ogilvie I., El Khoury A. C., Duan Y., Goetghebeur M. M. 2011; Burden of rotavirus gastroenteritis in the Middle Eastern and North African pediatric population. BMC Infect Dis 11:9 [View Article][PubMed]
    [Google Scholar]
  24. Kobayashi N., Lintag I. C., Urasawa T., Taniguchi K., Saniel M. C., Urasawa S. 1989; Unusual human rotavirus strains having subgroup I specificity and “long” RNA electropherotype. Arch Virol 109:11–23 [View Article][PubMed]
    [Google Scholar]
  25. Madhi S. A., Cunliffe N. A., Steele D., Witte D., Kirsten M., Louw C., Ngwira B., Victor J. C., Gillard P. H. et al. 2010; Effect of human rotavirus vaccine on severe diarrhea in African infants. N Engl J Med 362:289–298 [View Article][PubMed]
    [Google Scholar]
  26. Martella V., Potgieter A. C., Lorusso E., De Grazia S., Giammanco G. M., Matthijnssens J., Bányai K., Ciarlet M., Lavazza A. et al. 2011; A feline rotavirus G3P[9] carries traces of multiple reassortment events and resembles rare human G3P[9] rotaviruses. J Gen Virol 92:1214–1221 [View Article][PubMed]
    [Google Scholar]
  27. Matthijnssens J., Rahman M., Yang X., Delbeke T., Arijs I., Kabue J. P., Muyembe J. J., Van Ranst M. 2006; G8 rotavirus strains isolated in the Democratic Republic of Congo belong to the DS-1-like genogroup. J Clin Microbiol 44:1801–1809 [View Article][PubMed]
    [Google Scholar]
  28. Matthijnssens J., Ciarlet M., Heiman E., Arijs I., Delbeke T., McDonald S. M., Palombo E. A., Iturriza-Gómara M., Maes P. et al. 2008a; Full genome-based classification of rotaviruses reveals a common origin between human Wa-Like and porcine rotavirus strains and human DS-1-like and bovine rotavirus strains. J Virol 82:3204–3219 [View Article][PubMed]
    [Google Scholar]
  29. Matthijnssens J., Ciarlet M., Rahman M., Attoui H., Bányai K., Estes M. K., Gentsch J. R., Iturriza-Gómara M., Kirkwood C. D. et al. 2008b ). Recommendations for the classification of group A rotaviruses using all 11 genomic RNA segments. Arch Virol 153:1621–1629 [View Article][PubMed]
    [Google Scholar]
  30. Matthijnssens J., Rahman M., Van Ranst M. 2008c ). Two out of the 11 genes of an unusual human G6P[6] rotavirus isolate are of bovine origin. J Gen Virol 89:2630–2635 [View Article][PubMed]
    [Google Scholar]
  31. Matthijnssens J., Potgieter C. A., Ciarlet M., Parreño V., Martella V., Bányai K., Garaicoechea L., Palombo E. A., Novo L. et al. 2009; Are human P[14] rotavirus strains the result of interspecies transmissions from sheep or other ungulates that belong to the mammalian order Artiodactyla?. J Virol 83:2917–2929 [View Article][PubMed]
    [Google Scholar]
  32. Matthijnssens J., Heylen E., Zeller M., Rahman M., Lemey P., Van Ranst M. 2010; Phylodynamic analyses of rotavirus genotypes G9 and G12 underscore their potential for swift global spread. Mol Biol Evol 27:2431–2436 [View Article][PubMed]
    [Google Scholar]
  33. Mulherin E., Bryan J., Beltman M., O’Grady L., Pidgeon E., Garon L., Lloyd A., Bainbridge J., O’Shea H. et al. 2008; Molecular characterisation of a bovine-like rotavirus detected from a giraffe. BMC Vet Res 4:46 [View Article][PubMed]
    [Google Scholar]
  34. Mwenda J. M., Ntoto K. M., Abebe A., Enweronu-Laryea C., Amina I., Mchomvu J., Kisakye A., Mpabalwani E. M., Pazvakavambwa I. et al. 2010; Burden and epidemiology of rotavirus diarrhea in selected African countries: preliminary results from the African Rotavirus Surveillance Network. J Infect Dis 202:(Suppl.)S5–S11 [View Article][PubMed]
    [Google Scholar]
  35. Nyangao J., Page N., Esona M., Peenze I., Gatheru Z., Tukei P., Steele A. D. 2010; Characterization of human rotavirus strains from children with diarrhea in Nairobi and Kisumu, Kenya, between 2000 and 2002. J Infect Dis 202:(Suppl.)S187–S192 [View Article][PubMed]
    [Google Scholar]
  36. Potgieter A. C., Page N. A., Liebenberg J., Wright I. M., Landt O., van Dijk A. A. 2009; Improved strategies for sequence-independent amplification and sequencing of viral double-stranded RNA genomes. J Gen Virol 90:1423–1432 [View Article][PubMed]
    [Google Scholar]
  37. Rahman M., Matthijnssens J., Yang X., Delbeke T., Arijs I., Taniguchi K., Iturriza-Gómara M., Iftekharuddin N., Azim T., Van Ranst M. 2007; Evolutionary history and global spread of the emerging g12 human rotaviruses. J Virol 81:2382–2390 [View Article][PubMed]
    [Google Scholar]
  38. Saitou N., Nei M. 1987; The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol Biol Evol 4:406–425[PubMed]
    [Google Scholar]
  39. Sanchez-Padilla E., Grais R. F., Guerin P. J., Steele A. D., Burny M. E., Luquero F. J. 2009; Burden of disease and circulating serotypes of rotavirus infection in sub-Saharan Africa: systematic review and meta-analysis. Lancet Infect Dis 9:567–576 [View Article][PubMed]
    [Google Scholar]
  40. Santos N., Hoshino Y. 2005; Global distribution of rotavirus serotypes/genotypes and its implication for the development and implementation of an effective rotavirus vaccine. Rev Med Virol 15:29–56 [View Article][PubMed]
    [Google Scholar]
  41. Schumann T., Hotzel H., Otto P., Johne R. 2009; Evidence of interspecies transmission and reassortment among avian group A rotaviruses. Virology 386:334–343 [View Article][PubMed]
    [Google Scholar]
  42. Solberg O. D., Hasing M. E., Trueba G., Eisenberg J. N. 2009; Characterization of novel VP7, VP4, and VP6 genotypes of a previously untypeable group A rotavirus. Virology 385:58–67 [View Article][PubMed]
    [Google Scholar]
  43. Todd S., Page N. A., Duncan Steele A., Peenze I., Cunliffe N. A. 2010; Rotavirus strain types circulating in Africa: review of studies published during 1997–2006. J Infect Dis 202:(Suppl.)S34–S42 [View Article][PubMed]
    [Google Scholar]
  44. Urasawa S., Urasawa T., Taniguchi K., Chiba S. 1984; Serotype determination of human rotavirus isolates and antibody prevalence in pediatric population in Hokkaido, Japan. Arch Virol 81:1–12 [View Article][PubMed]
    [Google Scholar]
  45. Urasawa T., Urasawa S., Chiba Y., Taniguchi K., Kobayashi N., Mutanda L. N., Tukei P. M. 1987; Antigenic characterization of rotaviruses isolated in Kenya from 1982 to 1983. J Clin Microbiol 25:1891–1896[PubMed]
    [Google Scholar]
  46. Ursu K., Kisfali P., Rigó D., Ivanics E., Erdélyi K., Dán A., Melegh B., Martella V., Bányai K. 2009; Molecular analysis of the VP7 gene of pheasant rotaviruses identifies a new genotype, designated G23. Arch Virol 154:1365–1369 [View Article][PubMed]
    [Google Scholar]
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