Natural and experimental infection of dogs with pandemic H1N1/2009 influenza virus
Lin, Degui and Sun, Shasha and Du, Lijie and Ma, Jingjiao and Fan, Linghong and Pu, Juan and Sun, Yipeng and Zhao, Jingyi and Sun, Honglei and Liu, Jinhua,, 93, 119-123 (2012),
doi = https://doi.org/10.1099/vir.0.037358-0,
publicationName = Microbiology Society,
issn = 0022-1317,
abstract= Evidence of H1N1/2009 influenza virus infection was identified in two domestic dogs in China in November 2009. Virus isolation and sequence analysis of all eight genes of the two isolates showed that they were related closely to the H1N1/2009 influenza virus circulating in humans, indicating that they were probably acquired from humans. To determine the pathogenicity and transmissibility of H1N1/2009 influenza virus in dogs, experimental infection and transmission were performed. Inoculated dogs were able to shed virus in nasal secretions, but symptoms were very mild. Uninoculated dogs were co-mingled to determine the transmissibility of the isolate, and one of three exposed dogs was shown to develop infection. The present findings indicate that human H1N1/2009 can infect dogs, but is transmitted inefficiently between dogs.,
language=,
type=