@article{mbs:/content/journal/jgv/10.1099/vir.0.068403-0, author = "My, Phan Vu Tra and Rabaa, Maia A. and Donato, Celeste and Cowley, Daniel and Phat, Voong Vinh and Dung, Tran Thi Ngoc and Anh, Pham Hong and Vinh, Ha and Bryant, Juliet E. and Kellam, Paul and Thwaites, Guy and Woolhouse, Mark E. J. and Kirkwood, Carl D. and Baker, Stephen", title = "Novel porcine-like human G26P[19] rotavirus identified in hospitalized paediatric diarrhoea patients in Ho Chi Minh City, Vietnam", journal= "Journal of General Virology", year = "2014", volume = "95", number = "12", pages = "2727-2733", doi = "https://doi.org/10.1099/vir.0.068403-0", url = "https://www.microbiologyresearch.org/content/journal/jgv/10.1099/vir.0.068403-0", publisher = "Microbiology Society", issn = "1465-2099", type = "Journal Article", abstract = "During a hospital-based diarrhoeal disease study conducted in Ho Chi Minh City, Vietnam from 2009 to 2010, we identified four symptomatic children infected with G26P[19] rotavirus (RV) – an atypical variant that has not previously been reported in human gastroenteritis. To determine the genetic structure and investigate the origin of this G26P[19] strain, the whole genome of a representative example was characterized, revealing a novel genome constellation: G26–P[19]–I5–R1–C1–M1–A8–N1–T1–E1–H1. The genome segments were most closely related to porcine (VP7, VP4, VP6 and NSP1) and Wa-like porcine RVs (VP1–3 and NSP2–5). We proposed that this G26P[19] strain was the product of zoonotic transmission coupled with one or more reassortment events occurring in human and/or animal reservoirs. The identification of such strains has potential implications for vaccine efficacy in south-east Asia, and outlines the utility of whole-genome sequencing for studying RV diversity and zoonotic potential during disease surveillance.", }