@article{mbs:/content/journal/jgv/10.1099/vir.0.19054-0, author = "de Jesus, Orlando and Smith, Paul R. and Spender, Lindsay C. and Elgueta Karstegl, Claudio and Niller, Hans Helmut and Huang, Dolly and Farrell, Paul J.", title = "Updated Epstein–Barr virus (EBV) DNA sequence and analysis of a promoter for the BART (CST, BARF0) RNAs of EBV", journal= "Journal of General Virology", year = "2003", volume = "84", number = "6", pages = "1443-1450", doi = "https://doi.org/10.1099/vir.0.19054-0", url = "https://www.microbiologyresearch.org/content/journal/jgv/10.1099/vir.0.19054-0", publisher = "Microbiology Society", issn = "1465-2099", type = "Journal Article", abstract = "Two sequences required for activity of the Epstein–Barr virus BART RNA promoter in transfection assays have been identified by site-directed mutagenesis. One contains a consensus AP-1 site; the other has some similarity to Ets and Stat consensus binding sites. Candidate sequences were suggested by mapping a region of unmethylated DNA in EBV around the BART promoter followed by in vivo footprinting the promoter in the C666-1 nasopharyngeal carcinoma cell line, which expresses BART RNAs. The data are presented in the context of a revised EBV DNA sequence, known as EBV wt, that is proposed as a future standard sequence for EBV.", }