%0 Journal Article %A de Jesus, Orlando %A Smith, Paul R. %A Spender, Lindsay C. %A Elgueta Karstegl, Claudio %A Niller, Hans Helmut %A Huang, Dolly %A Farrell, Paul J. %T Updated Epstein–Barr virus (EBV) DNA sequence and analysis of a promoter for the BART (CST, BARF0) RNAs of EBV %D 2003 %J Journal of General Virology, %V 84 %N 6 %P 1443-1450 %@ 1465-2099 %R https://doi.org/10.1099/vir.0.19054-0 %I Microbiology Society, %X Two sequences required for activity of the Epstein–Barr virus BART RNA promoter in transfection assays have been identified by site-directed mutagenesis. One contains a consensus AP-1 site; the other has some similarity to Ets and Stat consensus binding sites. Candidate sequences were suggested by mapping a region of unmethylated DNA in EBV around the BART promoter followed by in vivo footprinting the promoter in the C666-1 nasopharyngeal carcinoma cell line, which expresses BART RNAs. The data are presented in the context of a revised EBV DNA sequence, known as EBV wt, that is proposed as a future standard sequence for EBV. %U https://www.microbiologyresearch.org/content/journal/jgv/10.1099/vir.0.19054-0