Influence of residue 44 on the activity of the M2 proton channel of influenza A virus

References

1. Chizhmakov I. V., Geraghty F. M., Ogden D. C., Hayhurst A., Antoniou M., Hay A. J. 1996; Selective proton permeability and pH regulation of the influenza virus M2 channel expressed in mouse erythroleukaemia cells. J Physiol 494:329–336 [CrossRef]
   [Google Scholar]
2. Chizhmakov I. V., Ogden D. C., Geraghty F. M., Hayhurst A., Skinner A., Betakova T., Hay A. J. 2003; Differences in conductance of M2 proton channels of two influenza viruses at low and high pH. J Physiol 546:427–438 [CrossRef]
   [Google Scholar]
3. Ciampor F., Bayley P. M., Nermut M. V., Hirst E. M. A., Sugrue R. J., Hay A. J. 1992; Evidence that the amantadine-induced, M2-mediated conversion of influenza A virus hemagglutinin to the low pH conformation occurs in an acidic trans Golgi compartment. Virology 188:14–24 [CrossRef]
   [Google Scholar]
4. Fuerst T. R., Niles E. G., Studier F. W., Moss B. 1986; Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase. Proc Natl Acad Sci U S A 83:8122–8126 [CrossRef]
   [Google Scholar]
5. Grambas S., Hay A. J. 1992; Maturation of influenza A virus hemagglutinin – estimates of the pH encountered during transport and its regulation by the M2 protein. Virology 190:11–18 [CrossRef]
   [Google Scholar]
6. Grambas S., Bennett M. S., Hay A. J. 1992; Influence of amantadine resistance mutations on the pH regulatory function of the M2 protein of influenza A viruses. Virology 191:541–549 [CrossRef]
   [Google Scholar]
7. Martin K., Helenius A. 1991; Nuclear transport of influenza virus ribonucleoproteins: the viral matrix protein (M1) promotes export and inhibits import. Cell 67:117–130 [CrossRef]
   [Google Scholar]
8. Mould J. A., Drury J. E., Frings S. M., Kaupp U. B., Pekosz A., Lamb R. A., Pinto L. H. 2000; Permeation and activation of the M₂ ion channel of influenza A virus. J Biol Chem 275:31038–31050 [CrossRef]
   [Google Scholar]
9. Pinto L. H., Holsinger L. J., Lamb R. A. 1992; Influenza virus M₂ protein has ion channel activity. Cell 69:517–528 [CrossRef]
   [Google Scholar]
10. Steinhauer D. A., Wharton S. A., Skehel J. J., Wiley D. C., Hay A. J. 1991; Amantadine selection of a mutant influenza virus containing an acid-stable hemagglutinin glycoprotein: evidence for virus-specific regulation of the pH of glycoprotein transport vesicles. Proc Natl Acad Sci U S A 88:11525–11529 [CrossRef]
    [Google Scholar]
11. Sugrue R. J., Bahadur G., Zambon M. C., Hall-Smith M., Douglas A. R., Hay A. J. 1990; Specific structural alteration of the influenza haemagglutinin by amantadine. EMBO J 9:3469–3476
    [Google Scholar]
12. Wharton S. A., Belshe R. B., Skehel J. J., Hay A. J. 1994; Role of virion M2 protein in influenza virus uncoating: specific reduction in the rate of membrane fusion between virus and liposomes by amantadine. J Gen Virol 75:945–948 [CrossRef]
    [Google Scholar]