1887

Abstract

The genus of the family includes the Crimean-Congo haemorrhagic fever (CCHF) species group. The species is predominated by the hazard-group 4 pathogens, from which the name and majority of strain entries are derived. Additionally, the species embraces hazard-group 2 viruses that are classified as members by antigenic cross-reactivity. CCHF viruses have a tripartite RNA genome consisting of large (L), medium (M) and small (S) segments. Here, the sequence characterization of previously undescribed L and S segments from novel strains originating in the Middle East and Africa is reported. Further scrutiny of this data with phylogenetic tools, in the context of other publicly available sequence information, reveals analogous grouping patterns between the L and S segments. These groups correlate with the geographical distribution of strain isolation and indicate that the L and S segments of CCHF viruses have evolved together.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/vir.0.81213-0
2005-12-01
2024-03-29
Loading full text...

Full text loading...

/deliver/fulltext/jgv/86/12/3337.html?itemId=/content/journal/jgv/10.1099/vir.0.81213-0&mimeType=html&fmt=ahah

References

  1. Al-Tikriti S. K., Al-Ani F., Jurji F. J. 12 other authors 1981; Congo/Crimean haemorrhagic fever in Iraq. Bull W H O 59:85–90
    [Google Scholar]
  2. Casals J. 1969; Antigenic similarity between the virus causing Crimean hemorrhagic fever and Congo virus. Proc Soc Exp Biol Med 131:233–236 [CrossRef]
    [Google Scholar]
  3. Casals J., Henderson B. E., Hoogstraal H., Johnson K. M., Shelokov A. 1970; A review of Soviet viral hemorrhagic fevers, 1969. J Infect Dis 122:437–453 [CrossRef]
    [Google Scholar]
  4. Causey O. R., Kemp G. E., Madbouly M. H., David-West T. S. 1970; Congo virus from domestic livestock, African hedgehog, and arthropods in Nigeria. Am J Trop Med Hyg 19:846–850
    [Google Scholar]
  5. Chare E. R., Gould E. A., Holmes E. C. 2003; Phylogenetic analysis reveals a low rate of homologous recombination in negative-sense RNA viruses. J Gen Virol 84:2691–2703 [CrossRef]
    [Google Scholar]
  6. Chumakov M. P. 1945; A new tick-borne virus disease – Crimean hemorrhagic fever. In Crimean hemorrhagic fever pp  13–43 Edited by Sokolov A. A., Chumakov M. P., Kolachev A. A. Simferopol: Izdaniye Otdelnoi Primorskoi Armii (in Russian
    [Google Scholar]
  7. Chumakov M. P., Butenko A. M., Shalunova N. V. 10 other authors 1968; New data on the viral agent of Crimean hemorrhagic fever. Vopr Virusol 13:377 (in Russian
    [Google Scholar]
  8. Drosten C., Minnak D., Emmerich P., Schmitz H., Reinicke T. 2002; Crimean-Congo hemorrhagic fever in Kosovo. J Clin Microbiol 40:1122–1123 [CrossRef]
    [Google Scholar]
  9. Elliott R. M., Bouloy M., Calisher C. H., Goldbach R., Moyer J. T., Nichol S. T., Pettersson R., Plyusnin A., Schmaljohn C. S. 2000; Family Bunyaviridae . In Seventh Report of the International Committee on Taxonomy of Viruses pp  599–621 Edited by van Regenmortel M. H. V., Fauquet C. M., Bishop D. H. L., Carstens E. B., Estes M. K., Lemon S. M., Maniloff J., Mayo M. A., McGeoch D. J., Pringle C. R., Wickner R. B. San Diego: Academic Press;
    [Google Scholar]
  10. Gonzalez-Scarano F., Nathanson N. 1996; Bunyaviridae . In Fields Virology , 3rd edn. pp  1473–1504 Edited by Fields B. N., Knipe D. M., Howley P. M. Philadelphia, PA: Lippincott-Raven;
    [Google Scholar]
  11. Hewson R., Chamberlain J., Mioulet V. 9 other authors 2004a; Crimean-Congo haemorrhagic fever virus: sequence analysis of the small RNA segments from a collection of viruses world wide. Virus Res 102:185–189 [CrossRef]
    [Google Scholar]
  12. Hewson R., Gmyl A., Gmyl L., Smirnova S. E., Karganova G., Jamil B., Hasan R., Chamberlain J., Clegg C. 2004b; Evidence of segment reassortment in Crimean-Congo haemorrhagic fever virus. J Gen Virol 85:3059–3070 [CrossRef]
    [Google Scholar]
  13. Holmes E. C. 2004; The phylogeography of human viruses. Mol Ecol 13:745–756 [CrossRef]
    [Google Scholar]
  14. Honig J. E., Osborne J. C., Nichol S. T. 2004; Crimean–Congo hemorrhagic fever virus genome L RNA segment and encoded protein. Virology 321:29–35 [CrossRef]
    [Google Scholar]
  15. Hoogstraal H. 1979; The epidemiology of tick-borne Crimean-Congo hemorrhagic fever in Asia, Europe, and Africa. J Med Entomol 15:307–417 [CrossRef]
    [Google Scholar]
  16. Kinsella E., Martin S. G., Grolla A., Czub M., Feldmann H., Flick R. 2004; Sequence determination of the Crimean–Congo hemorrhagic fever virus L segment. Virology 321:23–28 [CrossRef]
    [Google Scholar]
  17. Klempa B., Schmidt H. A., Ulrich R., Kaluz S., Labuda M., Meisel H., Hjelle B., Krüger D. H. 2003; Genetic interaction between distinct Dobrava hantavirus subtypes in Apodemus agrarius and A. flavicollis in nature. J Virol 77:804–809 [CrossRef]
    [Google Scholar]
  18. Marriott A. C., Nuttall P. A. 1992; Comparison of the S RNA segments and nucleoprotein sequences of Crimean-Congo hemorrhagic fever, Hazara, and Dugbe viruses. Virology 189:795–799 [CrossRef]
    [Google Scholar]
  19. Page R. D. M. 1996; treeview: an application to display phylogenetic trees on personal computers. Comput Appl Biosci 12:357–358
    [Google Scholar]
  20. Pringle C. R., Lees J. F., Clark W., Elliott R. M. 1984; Genome subunit reassortment among bunyaviruses analysed by dot hybridization using molecularly cloned complementary DNA probes. Virology 135:244–256 [CrossRef]
    [Google Scholar]
  21. Rodriguez L. L., Maupin G. O., Ksiazek T. G. 8 other authors 1997; Molecular investigation of a multisource outbreak of Crimean-Congo hemorrhagic fever in the United Arab Emirates. Am J Trop Med Hyg 57:512–518
    [Google Scholar]
  22. Schmaljohn C. S., Hooper J. W. 2001 Bunyaviridae . In Fields Virology , 4th edn. pp  1581–1602 Edited by Knipe D. M., Howley P. M. Philadelphia, PA: Lippincott Williams & Wilkins;
    [Google Scholar]
  23. Schmidt H. A., Strimmer K., Vingron M., von Haeseler A. 2002; tree-puzzle: maximum likelihood phylogenetic analysis using quartets and parellel computing. Bioinformatics 18:502–504 [CrossRef]
    [Google Scholar]
  24. Strimmer K., von Haeseler A. 1997; Likelihood-mapping: a simple method to visualize phylogenetic content of a sequence alignment. Proc Natl Acad Sci U S A 94:6815–6819 [CrossRef]
    [Google Scholar]
  25. Swanepoel R., Struthers K., Shepherd A. J., McGillivray G. M., Nel M. J., Jupp P. G. 1983; Crimean-Congo hemorrhagic fever in South Africa. Am J Trop Med Hyg 32:1407–1415
    [Google Scholar]
  26. Thompson J. D., Higgins D. G., Gibson T. J. 1994; clustal w: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22:4673–4680 [CrossRef]
    [Google Scholar]
  27. Watts D. M., Kziasek T. G., Linthicum K. J., Hoogstraal H. 1988; Crimean-Congo hemorrhagic fever. In The Arboviruses . Epidemiology and Ecology vol. 2 pp  177–260 Edited by Monath T. P. Boca Raton, FL: CRC Press;
    [Google Scholar]
  28. Woodall J. P., Williams M. C., Simpson D. I. 1967; Congo virus: a hitherto undescribed virus occurring in Africa. II. Identification studies. East Afr Med J 44:93–98
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/vir.0.81213-0
Loading
/content/journal/jgv/10.1099/vir.0.81213-0
Loading

Data & Media loading...

Supplements

Supplementary material 1

PDF
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error