1887

Abstract

Bats represent the major source of human rabies cases in the New World. In the USA, most cases are associated with species that are not commonly found or reported rabid. To understand better the epidemiology and public health significance of potentially important bat species, a molecular study was performed on samples collected from naturally infected rabid western pipistrelle (), eastern pipistrelle () and silver-haired bats () from different regions of their geographical distribution in the USA. A 264 bp fragment at the 5′ end of the N gene coding region was sequenced and analysed in comparison with rabies virus variants circulating within other North American mammals. Phylogenetic analysis demonstrated that bats maintain a unique rabies virus variant. Preliminary data also suggest that and may harbour two different rabies virus variants (Ps and Ln) that are likely to be maintained independently by each bat species, which recently appear to have emerged as major vectors of human disease.

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2006-08-01
2024-03-29
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