@article{mbs:/content/journal/jgv/10.1099/vir.0.82011-0, author = "Georgsson, Gudmundur and Sigurdarson, Sigurdur and Brown, Paul", title = "Infectious agent of sheep scrapie may persist in the environment for at least 16 years", journal= "Journal of General Virology", year = "2006", volume = "87", number = "12", pages = "3737-3740", doi = "https://doi.org/10.1099/vir.0.82011-0", url = "https://www.microbiologyresearch.org/content/journal/jgv/10.1099/vir.0.82011-0", publisher = "Microbiology Society", issn = "1465-2099", type = "Journal Article", abstract = "In 1978, a rigorous programme was implemented to stop the spread of, and subsequently eradicate, sheep scrapie in Iceland. Affected flocks were culled, premises were disinfected and, after 2–3 years, restocked with lambs from scrapie-free areas. Between 1978 and 2004, scrapie recurred on 33 farms. Nine of these recurrences occurred 14–21 years after culling, apparently as the result of environmental contamination, but outside entry could not always be absolutely excluded. Of special interest was one farm with a small, completely self-contained flock where scrapie recurred 18 years after culling, 2 years after some lambs had been housed in an old sheep-house that had never been disinfected. Epidemiological investigation established with near certitude that the disease had not been introduced from the outside and it is concluded that the agent may have persisted in the old sheep-house for at least 16 years.", }