Identification and genetic diversity of two human parvovirus B19 genotype 3 subtypes
Parsyan, Armen and Szmaragd, Camille and Allain, Jean-Pierre and Candotti, Daniel,, 88, 428-431 (2007),
doi = https://doi.org/10.1099/vir.0.82496-0,
publicationName = Microbiology Society,
issn = 0022-1317,
abstract= Three genotypes (1–3) of human parvovirus B19 have been identified. Analysis of 13 nearly full-length genotype 3 sequences from Ghana, Europe and Brazil identified two genetically distinct clusters. The classification of genotype 3 strains into two subtypes (B19/3a and B19/3b) is proposed. The rate of evolutionary change of B19 genotype 3 strains (2×10−4 nucleotide substitutions per site per year) was similar to those of B19 genotype 1 and carnivore parvoviruses, supporting the hypothesis that high mutation rates are characteristic of members of the family Parvoviridae. The estimated divergence time between B19/3a and B19/3b is 525 years. In Ghana, subtype B19/3a is predominant.,
language=,
type=