1887

Abstract

Three genotypes (1–3) of human parvovirus B19 have been identified. Analysis of 13 nearly full-length genotype 3 sequences from Ghana, Europe and Brazil identified two genetically distinct clusters. The classification of genotype 3 strains into two subtypes (B19/3a and B19/3b) is proposed. The rate of evolutionary change of B19 genotype 3 strains (2×10 nucleotide substitutions per site per year) was similar to those of B19 genotype 1 and carnivore parvoviruses, supporting the hypothesis that high mutation rates are characteristic of members of the family . The estimated divergence time between B19/3a and B19/3b is 525 years. In Ghana, subtype B19/3a is predominant.

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2007-02-01
2024-04-20
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References

  1. Blumel J., Eis-Hubinger A. M., Stuhler A., Bonsch C., Gessner M., Lower J. 2005; Characterization of parvovirus B19 genotype 2 in KU812Ep6 cells. J Virol 79:14197–14206 [CrossRef]
    [Google Scholar]
  2. Candotti D., Etiz N., Parsyan A., Allain J. P. 2004; Identification and characterization of persistent human erythrovirus infection in blood donor samples. J Virol 78:12169–12178 [CrossRef]
    [Google Scholar]
  3. Candotti D., Danso K., Parsyan A., Dompreh A., Allain J. P. 2006; Maternal-fetal transmission of human parvovirus B19 genotype 3. J Infect Dis 194:608–611 [CrossRef]
    [Google Scholar]
  4. Cohen B. J., Gandhi J., Clewley J. P. 2006; Genetic variants of parvovirus B19 identified in the United Kingdom: implications for diagnostic testing. J Clin Virol 36:152–155 [CrossRef]
    [Google Scholar]
  5. Gallinella G., Venturoli S., Manaresi E., Musiani M., Zerbini M. 2003; B19 virus genome diversity: epidemiological and clinical correlations. J Clin Virol 28:1–13 [CrossRef]
    [Google Scholar]
  6. Heegaard E. D., Brown K. E. 2002; Human parvovirus B19. Clin Microbiol Rev 15:485–505 [CrossRef]
    [Google Scholar]
  7. Heegaard E. D., Petersen B. L., Heilmann C. J., Hornsleth A. 2002; Prevalence of parvovirus B19 and parvovirus V9 DNA and antibodies in paired bone marrow and serum samples from healthy individuals. J Clin Microbiol 40:933–936 [CrossRef]
    [Google Scholar]
  8. Kerr J. R. 2005; Pathogenesis of parvovirus B19 infection: host gene variability, and possible means and effects of virus persistence. J Vet Med B Infect Dis Vet Public Health 52:335–339 [CrossRef]
    [Google Scholar]
  9. Lefrere J. J., Servant-Delmas A., Candotti D., Mariotti M., Thomas I., Brossard Y., Lefrere F., Girot R., Allain J. P., Laperche S. 2005; Persistent B19 infection in immunocompetent individuals: implications for transfusion safety. Blood 106:2890–2895 [CrossRef]
    [Google Scholar]
  10. Lukashov V. V., Goudsmit J. 2001; Evolutionary relationships among parvoviruses: virus-host coevolution among autonomous primate parvoviruses and links between adeno-associated and avian parvoviruses. J Virol 75:2729–2740 [CrossRef]
    [Google Scholar]
  11. Nguyen Q. T., Sifer C., Schneider V., Allaume X., Servant A., Bernaudin F., Auguste V., Garbarg-Chenon A. 1999; Novel human erythrovirus associated with transient aplastic anemia. J Clin Microbiol 37:2483–2487
    [Google Scholar]
  12. Parsyan A., Addo-Yobo E., Owusu-Ofori S., Akpene H., Sarkodie F., Allain J.-P. 2006a; Effects of transfusion on human erythrovirus B19-susceptible or -infected pediatric recipients in a genotype 3–endemic area. Transfusion 46:1593–1600 [CrossRef]
    [Google Scholar]
  13. Parsyan A., Kerr S., Owusu-Ofori S., Elliott G., Allain J. P. 2006b; Reactivity of genotype-specific recombinant proteins of human erythrovirus B19 with plasmas from areas where genotype 1 or 3 is endemic. J Clin Microbiol 44:1367–1375 [CrossRef]
    [Google Scholar]
  14. Sanabani S., Neto W. K., Pereira J., Sabino E. C. 2006; Sequence variability of human erythroviruses present in bone marrow of Brazilian patients with various parvovirus B19-related hematological symptoms. J Clin Microbiol 44:604–606 [CrossRef]
    [Google Scholar]
  15. Servant A., Laperche S., Lallemand F., Marinho V., De Saint Maur G., Meritet J. F., Garbarg-Chenon A. 2002; Genetic diversity within human erythroviruses: identification of three genotypes. J Virol 76:9124–9134 [CrossRef]
    [Google Scholar]
  16. Shackelton L. A., Holmes E. C. 2006; Phylogenetic evidence for the rapid evolution of human B19 erythrovirus. J Virol 80:3666–3669 [CrossRef]
    [Google Scholar]
  17. Shackelton L. A., Parrish C. R., Truyen U., Holmes E. C. 2005; High rate of viral evolution associated with the emergence of carnivore parvovirus. Proc Natl Acad Sci U S A 102:379–384 [CrossRef]
    [Google Scholar]
  18. Simmonds P. 2001). 2000; Fleming Lecture. The origin and evolution of hepatitis viruses in humans. J Gen Virol 82:693–712
    [Google Scholar]
  19. Swofford D. L., Sullivan J. 2003; Phylogenetic inference based on parsimony and other methods using paup*. In The Phylogenetic Handbook: A Practical Approach to DNA and Protein Phylogeny . pp  160–196 Edited by Salemi M., Vandamme A.-M. Cambridge: Cambridge University Press;
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