On the Nature of Poliovirus Genetic Recombinants Cooper, P. D. and Steiner-Pryor, A. and Scotti, P. D. and Delong, D.,, 23, 41-49 (1974), doi = https://doi.org/10.1099/0022-1317-23-1-41, publicationName = Microbiology Society, issn = 0022-1317, abstract= SUMMARY Recombinant and parental poliovirus particles were indistinguishable by ratezonal and isopycnic sedimentation, and by u.v. inactivation. Sensitive selective procedures, applied to ts + recombinants to detect genetic segregation of one parent, failed to reveal any. Poliovirus genetic recombinant particles thus appear to be conventional virus particles; their significance for recombination mechanisms is discussed. Sensitivity to the growth inhibitor 2-(3-chloro-p-tolyl)-5-ethyl-1,3,4-oxadiazole is shown to depend on a product of the structural protein gene., language=, type=