Evaluation of Human and Simian Immunodeficiency Virus Plaque and Neutralization Assays
McKeating*, J. A. and McKnight, A. and McIntosh, K. and Clapham, P. R. and Mulder, C. and Weiss, R. A.,, 70, 3327-3333 (1989),
doi = https://doi.org/10.1099/0022-1317-70-12-3327,
publicationName = Microbiology Society,
issn = 0022-1317,
abstract= SUMMARY A number of CD4+ T cell lines were compared for their ability to act as target cells for human immunodeficiency virus (HIV) infection in syncytium- and plaque-forming assays. MT-4 and C8166 cells were the most sensitive indicator cells for HIV- and simian immunodeficiency virus (SIV)-induced cytopathic effects, and gave rise to macroscopic (MT-4) and microscopic (C8166) plaques. The MT-4 plaque assay was evaluated for the measurement of HIV- and SIV-neutralizing antibodies.,
language=,
type=