Cytopathic and Non-cytopathic Biotypes of Border Disease Virus Induce Polypeptides of Different Molecular Weight with Common Antigenic Determinants
Dutia, Bernadette M. and Entrican, Gary and Nettleton, Peter F.,, 71, 1227-1232 (1990),
doi = https://doi.org/10.1099/0022-1317-71-5-1227,
publicationName = Microbiology Society,
issn = 0022-1317,
abstract= Ten monoclonal antibodies have been raised against lysates of cells infected with cytopathic border disease virus (BDV). These antibodies all recognize non- cytopathic BDV and react with a number of different strains of bovine viral diarrhoea virus (BVDV). Studies with radiolabelled cell lysates show that all the antibodies precipitate two polypeptides of apparent M r 80000 and 130000 from cells infected with cytopathic virus and a single polypeptide of apparent M r 120000 from cells infected with non-cytopathic virus. Two of the monoclonal antibodies react on immunoblots and show the same pattern of reactivity indicating that these three polypeptides are antigenically related.,
language=,
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