@article{mbs:/content/journal/jgv/10.1099/0022-1317-73-6-1547, author = "Allan, Gordon J. and Inman, Gareth J. and Parker, Bruce D. and Rowe, David T. and Farrell, Paul J.", title = "Cell growth effects of Epstein—Barr virus leader protein", journal= "Journal of General Virology", year = "1992", volume = "73", number = "6", pages = "1547-1551", doi = "https://doi.org/10.1099/0022-1317-73-6-1547", url = "https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-73-6-1547", publisher = "Microbiology Society", issn = "1465-2099", type = "Journal Article", abstract = "B lymphoblastoid cell lines immortalized with P3HR1/633 Epstein—Barr virus (EBV), which has a deletion in the EBV nuclear antigen leader protein (EBNA-LP) gene, were transfected with a vector expressing wild-type EBNA-LP. The EBNA-LP trans-fectants grew out faster under G418 selection than control cells but expression of EBNA-LP made no significant difference to growth rate or saturation density of the resulting established cell lines. When the cells expressing EBNA-LP were allowed to grow to saturation and then diluted in fresh medium they underwent DNA synthesis more rapidly than control cultures.", }