Cell growth effects of Epstein—Barr virus leader protein Allan, Gordon J. and Inman, Gareth J. and Parker, Bruce D. and Rowe, David T. and Farrell, Paul J.,, 73, 1547-1551 (1992), doi = https://doi.org/10.1099/0022-1317-73-6-1547, publicationName = Microbiology Society, issn = 0022-1317, abstract= B lymphoblastoid cell lines immortalized with P3HR1/633 Epstein—Barr virus (EBV), which has a deletion in the EBV nuclear antigen leader protein (EBNA-LP) gene, were transfected with a vector expressing wild-type EBNA-LP. The EBNA-LP trans-fectants grew out faster under G418 selection than control cells but expression of EBNA-LP made no significant difference to growth rate or saturation density of the resulting established cell lines. When the cells expressing EBNA-LP were allowed to grow to saturation and then diluted in fresh medium they underwent DNA synthesis more rapidly than control cultures., language=, type=