@article{mbs:/content/journal/jgv/10.1099/jgv.0.000840, author = "Le Pendu, Jacques and Abrantes, Joana and Bertagnoli, Stéphane and Guitton, Jean-Sébastien and Le Gall-Reculé, Ghislaine and Lopes, Ana Margarida and Marchandeau, Stéphane and Alda, Fernando and Almeida, Tereza and Célio, Alves Paulo and Bárcena, Juan and Burmakina, Galina and Blanco, Esther and Calvete, Carlos and Cavadini, Patrizia and Cooke, Brian and Dalton, Kevin and Delibes Mateos, Miguel and Deptula, Wieslaw and Eden, John Sebastian and Wang, Fang and Ferreira, Catarina C and Ferreira, Paula and Foronda, Pilar and Gonçalves, David and Gavier-Widén, Dolores and Hall, Robin and Hukowska-Szematowicz, Beata and Kerr, Peter and Kovaliski, John and Lavazza, Antonio and Mahar, Jackie and Malogolovkin, Alexander and Marques, Raquel M. and Marques, Sara and Martin-Alonso, Aaron and Monterroso, Pedro and Moreno, Sacramento and Mutze, Greg and Neimanis, Aleksija and Niedzwiedzka-Rystwej, Paulina and Peacock, David and Parra, Francisco and Rocchi, Mara and Rouco, Carlos and Ruvoën-Clouet, Nathalie and Silva, Eliane and Silvério, Diogo and Strive, Tanja and Thompson, Gertrudes and Tokarz-Deptula, Beata and Esteves, Pedro", title = "Proposal for a unified classification system and nomenclature of lagoviruses", journal= "Journal of General Virology", year = "2017", volume = "98", number = "7", pages = "1658-1666", doi = "https://doi.org/10.1099/jgv.0.000840", url = "https://www.microbiologyresearch.org/content/journal/jgv/10.1099/jgv.0.000840", publisher = "Microbiology Society", issn = "1465-2099", type = "Journal Article", keywords = "lagovirus", keywords = "nomenclature", keywords = "classification", keywords = "calicivirus", keywords = "RNA virus", keywords = "phylogeny", abstract = "Lagoviruses belong to the Caliciviridae family. They were first recognized as highly pathogenic viruses of the European rabbit (Oryctolagus cuniculus) and European brown hare (Lepus europaeus) that emerged in the 1970–1980s, namely, rabbit haemorrhagic disease virus (RHDV) and European brown hare syndrome virus (EBHSV), according to the host species from which they had been first detected. However, the diversity of lagoviruses has recently expanded to include new related viruses with varying pathogenicity, geographic distribution and host ranges. Together with the frequent recombination observed amongst circulating viruses, there is a clear need to establish precise guidelines for classifying and naming lagovirus strains. Therefore, here we propose a new nomenclature based on phylogenetic relationships. In this new nomenclature, a single species of lagovirus would be recognized and called Lagovirus europaeus. The species would be divided into two genogroups that correspond to RHDV- and EBHSV-related viruses, respectively. Genogroups could be subdivided into genotypes, which could themselves be subdivided into phylogenetically well-supported variants. Based on available sequences, pairwise distance cutoffs have been defined, but with the accumulation of new sequences these cutoffs may need to be revised. We propose that an international working group could coordinate the nomenclature of lagoviruses and any proposals for revision.", }