1887

Abstract

The , comprising one genus, , is a family of capsidless viruses with positive-sense, ssRNA genomes of 9.1–12.7 kb that possess either a single large ORF or two ORFs. The ORFs appear to be translated from genomic RNA by non-canonical mechanisms, i.e. internal ribosome entry site-mediated and stop/restart translation. Hypoviruses have been detected in ascomycetous or basidiomycetous filamentous fungi, and are considered to be replicated in host Golgi-derived, lipid vesicles that contain their dsRNA as a replicative form. Some hypoviruses induce hypovirulence to host fungi, while others do not. This is a summary of the current ICTV report on the taxonomy of the , which is available at www.ictv.global/report/hypoviridae.

Keyword(s): Hypoviridae , ICTV Report and Taxonomy
Loading

Article metrics loading...

/content/journal/jgv/10.1099/jgv.0.001055
2018-05-01
2024-03-28
Loading full text...

Full text loading...

/deliver/fulltext/jgv/99/5/615.html?itemId=/content/journal/jgv/10.1099/jgv.0.001055&mimeType=html&fmt=ahah

References

  1. Newhouse JR, Hoch HC, Macdonald WL. The ultrastructure of Endothia parasitica. Comparison of a virulent with a hypovirulent isolate. Can J Botany 1983; 61:389–399 [View Article]
    [Google Scholar]
  2. Fahima T, Wu Y, Zhang L, van Alfen NK. Identification of the putative RNA polymerase of Cryphonectria hypovirus in a solubilized replication complex. J Virol 1994; 68:6116–6119[PubMed]
    [Google Scholar]
  3. Hillman BI, Suzuki N. Viruses of the chestnut blight fungus, Cryphonectria parasitica. Adv Virus Res 2004; 63:423–472 [View Article][PubMed]
    [Google Scholar]
  4. Guo LH, Sun L, Chiba S, Araki H, Suzuki N. Coupled termination/reinitiation for translation of the downstream open reading frame B of the prototypic hypovirus CHV1-EP713. Nucleic Acids Res 2009; 37:3645–3659 [View Article][PubMed]
    [Google Scholar]
  5. Shapira R, Choi GH, Hillman BI, Nuss DL. The contribution of defective RNAs to the complexity of viral-encoded double-stranded RNA populations present in hypovirulent strains of the chestnut blight fungus Cryphonectria parasitica. EMBO J 1991; 10:741–746[PubMed]
    [Google Scholar]
  6. Yuan W, Hillman BI. In vitro translational analysis of genomic, defective, and satellite RNAs of Cryphonectria hypovirus 3-GH2. Virology 2001; 281:117–123 [View Article][PubMed]
    [Google Scholar]
  7. Nuss DL. Mycoviruses, RNA silencing, and viral RNA recombination. Adv Virus Res 2011; 80:25–48 [View Article][PubMed]
    [Google Scholar]
  8. Jensen KS, Nuss DL. Mutagenesis of the catalytic and cleavage site residues of the hypovirus papain-like proteases p29 and p48 reveals alternative processing and contributions to optimal viral RNA accumulation. J Virol 2014; 88:11946–11954 [View Article][PubMed]
    [Google Scholar]
  9. Marzano SY, Hobbs HA, Nelson BD, Hartman GL, Eastburn DM et al. Transfection of Sclerotinia sclerotiorum with in vitro transcripts of a naturally occurring interspecific recombinant of Sclerotinia sclerotiorum hypovirus 2 significantly reduces virulence of the fungus. J Virol 2015; 89:5060–5071 [View Article][PubMed]
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/jgv.0.001055
Loading
/content/journal/jgv/10.1099/jgv.0.001055
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error