%0 Journal Article %A Benzarti, Emna %A Linden, Annick %A Desmecht, Daniel %A Garigliany, Mutien %T Mosquito-borne epornitic flaviviruses: an update and review %D 2019 %J Journal of General Virology, %V 100 %N 2 %P 119-132 %@ 1465-2099 %R https://doi.org/10.1099/jgv.0.001203 %K birds %K flaviviruses %K vaccine %K mosquitoes %K epornitic %I Microbiology Society, %X West Nile Virus, Usutu virus, Bagaza virus, Israel turkey encephalitis virus and Tembusu virus currently constitute the five flaviviruses transmitted by mosquito bites with a marked pathogenicity for birds. They have been identified as the causative agents of severe neurological symptoms, drop in egg production and/or mortalities among avian hosts. They have also recently shown an expansion of their geographic distribution and/or a rise in cases of human infection. This paper is the first up-to-date review of the pathology of these flaviviruses in birds, with a special emphasis on the difference in susceptibility among avian species, in order to understand the specificity of the host spectrum of each of these viruses. Furthermore, given the lack of a clear prophylactic approach against these viruses in birds, a meta-analysis of vaccination trials conducted to date on these animals is given to constitute a solid platform from which designing future studies. %U https://www.microbiologyresearch.org/content/journal/jgv/10.1099/jgv.0.001203