Identification of a region of the virus genome involved in murine gammaherpesvirus 68-induced splenic pathology

References

1. Bowden R. J., Simas J. P., Davis A. J., Efstathiou S. 1997; Murine gammaherpesvirus 68 encodes tRNA-like sequences which are expressed during latency. J Gen Virol 78:1675–1687
   [Google Scholar]
2. Choi J. K., Lee B. S., Shim S. N., Li M., Jung J. U. 2000; Identification of the novel K15 gene at the rightmost end of the Kaposi's sarcoma-associated herpesvirus genome. J Virol 74:436–446 [CrossRef]
   [Google Scholar]
3. Christensen J. P., Cardin R. D., Branum K. C., Doherty P. C. 1999; CD4(+) T cell-mediated control of a gamma-herpesvirus in B cell-deficient mice is mediated by IFN-gamma. Proc Natl Acad Sci U S A 96:5135–5140 [CrossRef]
   [Google Scholar]
4. Clambey E. T., Virgin H. W. IV, Speck S. H. 2000; Disruption of the murine gammaherpesvirus 68 M1 open reading frame leads to enhanced reactivation from latency. J Virol 74:1973–1984 [CrossRef]
   [Google Scholar]
5. Dutia B. M., Clarke C. J., Allen D. J., Nash A. A. 1997; Pathological changes in the spleens of gamma interferon receptor-deficient mice infected with murine gammaherpesvirus: a role for CD8 T cells. J Virol 71:4278–4283
   [Google Scholar]
6. Ebrahimi B., Dutia B. M., Brownstein D. G., Nash A. A. 2001; Murine gammaherpesvirus-68 infection causes multi-organ fibrosis and alters leukocyte trafficking in interferon-gamma receptor knockout mice. Am J Pathol 158:2117–2125 [CrossRef]
   [Google Scholar]
7. Efstathiou S., Ho Y. M., Hall S., Styles C. J., Scott S. D., Gompels U. A. 1990; Murine herpesvirus 68 is genetically related to the gammaherpesviruses Epstein–Barr virus and herpesvirus saimiri. J Gen Virol 71:1365–1372 [CrossRef]
   [Google Scholar]
8. Flano E., Husain S. M., Sample J. T., Woodland D. L., Blackman M. A. 2000; Latent murine gamma-herpesvirus infection is established in activated B cells, dendritic cells, and macrophages. J Immunol 165:1074–1081 [CrossRef]
   [Google Scholar]
9. Huang S., Hendriks W., Althage A., Hemmi S., Bluethmann H., Kamijo R., Vilcek J., Zinkernagel R. M., Aguet M. 1993; Immune response in mice that lack the interferon- γ receptor. Science 259:1742–1745 [CrossRef]
   [Google Scholar]
10. Husain S. M., Usherwood E. J., Dyson H., Coleclough C., Coppola M. A., Woodland D. L., Blackman M. A., Stewart J. P., Sample J. T. 1999; Murine gammaherpesvirus M2 gene is latency-associated and its protein a target for CD8⁺ T lymphocytes. Proc Natl Acad Sci U S A 96:7508–7513 [CrossRef]
    [Google Scholar]
11. Laux G., Perricaudet M., Farrell P. J. 1988; A spliced Epstein–Barr virus gene expressed in immortalized lymphocytes is created by circularization of the linear viral genome. EMBO J 7:769–774
    [Google Scholar]
12. Macrae A. I., Dutia B. M., Milligan S., Brownstein D. G., Allen D. J., Mistrikova J., Davison A. J., Nash A. A., Stewart J. P. 2001; Analysis of a novel strain of murine gammaherpesvirus reveals a genomic locus important for acute pathogenesis. J Virol 75:5315–5327 [CrossRef]
    [Google Scholar]
13. Roy D. J., Ebrahimi B. C., Dutia B. M., Nash A. A., Stewart J. P. 2000; Murine gammaherpesvirus M11 gene product inhibits apoptosis and is expressed during virus persistence. Arch Virol 145:2411–2420 [CrossRef]
    [Google Scholar]
14. Sambrook J., Russell D. W. 2001 Molecular Cloning. a Laboratory Manual , 3rd edn. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory;
    [Google Scholar]
15. Sample J., Liebowitz D., Kieff E. 1989; Two related Epstein–Barr virus membrane proteins are encoded by separate genes. J Virol 63:933–937
    [Google Scholar]
16. Sarawar S. R., Cardin R. D., Brooks J. W., Mehrpooya M., Tripp R. A., Doherty P. C. 1996; Cytokine production in the immune response to murine gammaherpesvirus 68. J Virol 70:3264–3268
    [Google Scholar]
17. Simas J. P., Bowden R. J., Paige V., Efstathiou S. 1998; Four tRNA-like sequences and a serpin homologue encoded by murine gammaherpesvirus 68 are dispensable for lytic replication in vitro and latency in vivo . J Gen Virol 79:149–153
    [Google Scholar]
18. Stewart J. P., Usherwood E. J., Ross A., Dyson H., Nash T. 1998; Lung epithelial cells are a major site of murine gammaherpesvirus persistence. J Exp Med 187:1941–1951 [CrossRef]
    [Google Scholar]
19. Stoddart C. A., Cardin R. D., Boname J. M., Manning W. C., Abenes G. B., Mocarski E. S. 1994; Peripheral blood mononuclear phagocytes mediate dissemination of murine cytomegalovirus. J Virol 68:6243–6253
    [Google Scholar]
20. Sunil-Chandra N. P., Efstathiou S., Arno J., Nash A. A. 1992a; Virological and pathological features of mice infected with murine gamma-herpesvirus 68. J Gen Virol 73:2347–2356 [CrossRef]
    [Google Scholar]
21. Sunil-Chandra N. P., Efstathiou S., Nash A. A. 1992b; Murine gammaherpesvirus 68 establishes a latent infection in mouse B lymphocytes in vivo. J Gen Virol 73:3275–3279 [CrossRef]
    [Google Scholar]
22. Tripp R. A., Hamilton-Easton A. M., Cardin R. D., Nguyen P., Behm F. G., Woodland D. L., Doherty P. C., Blackman M. A. 1997; Pathogenesis of an infectious mononucleosis-like disease induced by a murine gamma-herpesvirus: role for a viral superantigen?. J Exp Med 185:1641–1650 [CrossRef]
    [Google Scholar]
23. Usherwood E. J., Roy D. J., Ward K., Surman S. L., Dutia B. M., Blackman M. A., Stewart J. P., Woodland D. L. 2000; Control of gammaherpesvirus latency by latent antigen-specific CD8⁺ T cells. J Exp Med 192:943–952 [CrossRef]
    [Google Scholar]
24. Virgin H. W., Latreille P., Wamsley P., Hallsworth K., Weck K. E., Dal Canto A. J., Speck S. H. 1997; Complete sequence and genomic analysis of murine gammaherpesvirus 68. J Virol 71:5894–5904
    [Google Scholar]
25. Weck K. E., Dal Canto A. J., Gould J. D., O'Guin A. K., Roth K. A., Saffitz J. E., Speck S. H., Virgin H. W. 1997; Murine gamma-herpesvirus 68 causes severe large-vessel arteritis in mice lacking interferon-gamma responsiveness: a new model for virus-induced vascular disease. Nat Med 3:1346–1353 [CrossRef]
    [Google Scholar]
26. Weck K. E., Kim S. S., Virgin H. I., Speck S. H. 1999; Macrophages are the major reservoir of latent murine gammaherpesvirus 68 in peritoneal cells. J Virol 73:3273–3283
    [Google Scholar]