1887

Abstract

Acid-stable equine picornaviruses (ASPs) were identified as a distinct serotype of equine picornaviruses that were isolated from nasal swabs taken from horses with acute febrile respiratory disease in the UK and Japan, and were placed in the group of unclassified picornaviruses. The nucleotide sequence of the P1 region, encoding the capsid proteins, was determined for three ASP isolates from the UK and the sequences were aligned with published sequences of (ERBV), genus , including acid-labile ERBV1 and ERBV2 and the recently identified acid-stable ERBV1. The ASPs belong to the same phylogenetic group, composed of five acid-stable ERBV1 isolates. ERBV1 rabbit antiserum neutralized the ASP isolates at approximately 1/10 titre relative to acid-stable and acid-labile ERBV1 isolates, supporting prior findings that ASPs are a distinct serotype, albeit cross-neutralizing weakly with ERBV1. The genus therefore presently comprises three serotypes: ERBV1, ERBV2 and the proposed ERBV3.

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2006-10-01
2024-04-19
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References

  1. Black W. D., Hartley C. A., Ficorilli N. P., Studdert M. J. 2005; Sequence variation divides Equine rhinitis B virus into three distinct phylogenetic groups that correlate with serotype and acid stability. J Gen Virol 86:2323–2332 [CrossRef]
    [Google Scholar]
  2. Burrows R. 1979; Equine rhinovirus and adenovirus infections. In Proceedings of the 24th Annual Convention of the American Association of Equine Practitioners pp  299–306 Edited by Smith J., Jones F., Dick A. St Louis, MS: American Association of Equine Practitioners;
    [Google Scholar]
  3. Fukunaga Y., Kumanomido T., Kamada K., Wada R. 1983; Equine picornavirus: isolation of virus from the oral cavity of healthy horses. Bull Equine Res Inst 20:103–109
    [Google Scholar]
  4. Hofer B., Steck F., Gerber H., Lohrer J., Nicolet J., Paccaud M. F. 1973; An investigation of the etiology of viral respiratory disease in a remount depot. In Proceedings of the Third International Conference on Equine Infectious Diseases pp  527–545 Edited by Bryans J. T., Gerber H. Basel, Switzerland: S. Karger;
    [Google Scholar]
  5. Huang J., Ficorilli N., Hartley C. A., Wilcox R. S., Weiss M., Studdert M. J. 2001; Equine rhinitis B virus: a new serotype. J Gen Virol 82:2641–2645
    [Google Scholar]
  6. Kriegshäuser G., Deutz A., Kuechler E., Skern T., Lussy H., Nowotny N. 2005; Prevalence of neutralizing antibodies to Equine rhinitis A and B virus in horses and man. Vet Microbiol 106:293–296 [CrossRef]
    [Google Scholar]
  7. Li F., Browning G. F., Studdert M. J., Crabb B. S. 1996; Equine rhinovirus 1 is more closely related to foot-and-mouth disease virus than to other picornaviruses. Proc Natl Acad Sci U S A 93:990–995 [CrossRef]
    [Google Scholar]
  8. Mumford J. A., Thomson G. R. 1978; Studies on picornaviruses isolated from the respiratory tract of horses. In Proceedings of the Fourth International Conference on Equine Infectious Diseases pp  419–429 Edited by Bryans J. T., Gerber H. Princeton, NJ: Veterinary Publications;
    [Google Scholar]
  9. Page R. D. M. 1996; TreeView: an application to display phylogenetic trees on personal computers. Comput Appl Biosci 12:357–358
    [Google Scholar]
  10. Plummer G. 1962; An equine respiratory virus with enterovirus properties. Nature 195:519–520 [CrossRef]
    [Google Scholar]
  11. Racaniello V. R. 2001; Picornaviridae : the viruses and their replication. In Fields Virology , 4th edn. pp  685–722 Edited by Knipe D. M., Howley P. M. Philadelphia, PA: Lippincott Williams & Wilkins;
    [Google Scholar]
  12. Stanway G., Brown F., Christian P. & 9 other authors 2005; Family Picornaviridae . In Virus Taxonomy: Eighth Report of the International Committee on Taxonomy of Viruses pp  757–778 Edited by Fauquet C. M., Mayo M. A., Maniloff J., Desselberger U., Ball L. A. San Diego: Elsevier Academic Press;
    [Google Scholar]
  13. Steck F., Hofer B., Schaeren B., Nicolet J., Gerber H. 1978; Equine rhinoviruses: new serotypes. In Proceedings of the Fourth International Conference on Equine Infectious Diseases pp  321–328 Edited by Bryans J. T., Gerber H. Princeton, NJ: Veterinary Publications;
    [Google Scholar]
  14. Studdert M. J., Gleeson L. J. 1978; Isolation and characterisation of an equine rhinovirus. Zentralbl Veterinarmed B 25:225–237
    [Google Scholar]
  15. Thompson J. D., Gibson T. J., Plewniak F., Jeanmougin F., Higgins D. G. 1997; The clustal_x windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res 25:4876–4882 [CrossRef]
    [Google Scholar]
  16. Varrasso A., Drummer H. E., Huang J. A., Stevenson R. A., Ficorilli N., Studdert M. J., Hartley C. A. 2001; Sequence conservation and antigenic variation of the structural proteins of equine rhinitis A virus. J Virol 75:10550–10556 [CrossRef]
    [Google Scholar]
  17. Wutz G., Auer H., Nowotny N., Grosse B., Skern T., Kuechler E. 1996; Equine rhinovirus serotypes 1 and 2: relationship to each other and to aphthoviruses and cardioviruses. J Gen Virol 77:1719–1730 [CrossRef]
    [Google Scholar]
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