1887

Abstract

SUMMARY

The replication of herpes simplex virus type 1 and herpes simplex virus type 2 was studied in two isolated hamster cell lines. These lines developed after being treated with herpes simplex virus type 2 inactivated with 7,12-dimethylbenz(a)-anthracene. One cell line that developed, HDC-22, had a hypodiploid chromosome number and was missing a D-group chromosome. Growth studies revealed that this cell line did not support the replication of herpes simplex virus type 2 but did support the replication of herpes simplex virus type 1. The other cell line, HDC-17, had a normal karyotype and proved susceptible to both herpes simplex virus type 1 and herpes simplex virus type 2. These hamster cell lines afford an opportunity to study specific resistance to herpes simplex virus and the differences in the replicative cycles of type 1 and type 2 herpesviruses.

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/content/journal/jgv/10.1099/0022-1317-13-3-377
1971-12-01
2024-05-07
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References

  1. Alford C., Snider M., Stubbs G. 1967; Studies on the virulence of herpes simplex viruses isolated from different clinical entities. Pediatric Research 1:209
    [Google Scholar]
  2. Black P. H. 1968; The oncogenic DNA viruses: a review of in vitro transformation studies. Annual Reviews of Microbiology 22:391
    [Google Scholar]
  3. Cassingena R., Tournier P. 1968; Mise en evidence d’un ‘represseur’ spécifique dans des cellules d’espèces différentes transformées par le virus SV40. Comptes rendus hebdomadaires des seances de l’ Académie des Sciences D 267:2251
    [Google Scholar]
  4. Docherty J. J., Goldberg R. J., Rapp F. 1971; . Differential effect of 7, 12-dimethylbenz(a)anthracene on infectivity of herpes simplex virus type 2. Proceedings of the Society for Experimental Biology and Medicine 136:328
    [Google Scholar]
  5. Duff R., Rapp F. 1970; Quantitative characteristics of the transformation of hamster cells by PARA (defective simian virus 4o)-adenovirus 7. Journal of Virology 5:568
    [Google Scholar]
  6. Figueroa M. E., Rawls W. E. 1969; Biological markers for differentiation of herpes-virus strains of oral and genital origin. Journal of General Virology 4:259
    [Google Scholar]
  7. Hsu T. C., Benirschke K. 1967; An atlas of mammalian chromosomes. Mesocricetus auratus (Syrian or ‘golden’ hamster) vol 1 p 14 New York, N.Y.: Springer-Verlag;
    [Google Scholar]
  8. Jensen F. C., Koprowski H. 1969; Absence of repressor in SV40-transformed cells. Virology 37:687
    [Google Scholar]
  9. Miles C. P., O’neill F. 1966; Prominent secondary constrictions in a pseudodiploid human cell line. Cytogenetics 5:321
    [Google Scholar]
  10. Nahmias A. J., Dowdle W. R., Naib Z. M., Highsmith A., Harwell R. W., Josey W. E. 1968; Relation of pock size on chorioallantoic membrane to antigenic type of herpesvirus hominis. Proceedings of the Society for Experimental Biology and Medicine 127:1022
    [Google Scholar]
  11. O’neill F. J., Miles C. P. 1969; Chromosome changes in human cells induced by herpes simplex, types 1and 2. Nature, London 223:851
    [Google Scholar]
  12. Pauls F. P., Dowdle W. R. 1967; A serologic study of herpesvirus hominis strains by microneutralization tests. Journal of Immunology 98:941
    [Google Scholar]
  13. Plummer G., Waner J. L., Phuangsab A., Goodheart C. R. 1970; Type I and type 2 herpes simplex viruses: serological and biological differences. Journal of Virology 5:51
    [Google Scholar]
  14. Ptashne M. 1967; Isolation of the A phage repressor. Proceedings of the National Academy of Science of the United States of America 57:306
    [Google Scholar]
  15. Rapp F., Trulock S. C. 1970; Susceptibility to superinfection of simian cells transformed by SV40. Virology 40:961
    [Google Scholar]
  16. Rawls W. E., Laurel D., Melnick J. L., Glicksman J. M., Kaufman R. H. 1968; A Search for viruses in smegma, premalignant and early malignant cervical tissues.The isolation of herpesviruses with distinct antigenic properties. American Journal of Epidemiology 87:647
    [Google Scholar]
  17. Robinson W. S., Pitkanen A., Rubin H. 1965; The nucleic acid of the bryan strain of Rous sarcoma virus: purification of the virus and isolation of the nucleic acid. Proceedings of the National Academy of Science of the United States of America 54:137
    [Google Scholar]
  18. Waubke R., Zur Hausen H., Henle W. 1968; Chromosomal and autoradiographic studies of cells infected with herpes simplex virus. Journal of Virology 2:1047
    [Google Scholar]
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