1887

Abstract

Summary

Camptothecin, an inhibitor of cellular nucleic acid synthesis, prevents fowl plague virus replication in BHK 21/13 cells. In the presence of camptothecin the synthesis of haemagglutinin and neuraminidase antigens does not occur; the ribonucleoprotein antigen is synthesized and accumulates only in the cell nucleus; and the synthesis of virus-specific RNA (of which complementary RNA predominates) is reduced considerably.

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/content/journal/jgv/10.1099/0022-1317-25-3-427
1974-12-01
2024-05-06
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