Are Cytotoxicity and Interferon Inducing Activity of Poly(I). Poly(C) Invariably Linked in Interferon-treated L cells? *

References

1. De Clercq E., De Somer P. 1971; Antiviral activity of polyribocytidylic acid in cells primed with poly- riboinosinic acid. Science, New York 173:260–262
   [Google Scholar]
2. De Clercq E., De Somer P. 1972a; Mechanism of the antiviral activity resulting from sequential administration of complementary homopolyribonucleotides to cell cultures. Journal of Virology 9:721–731
   [Google Scholar]
3. De Clercq E., De Somer P. 1972b; Production of interferon in rabbit cell cultures by mouse L cell-bound poly (rl).poly (rC). Journal of General Virology 16:435–439
   [Google Scholar]
4. De Clercq E., De Somer P. 1974; Interferon production in rabbit kidney cell cultures exposed to poly(I).poly(C) adsorbed to rabbit red blood cells. Journal of General Virology 22:271–275
   [Google Scholar]
5. De Clercq E., Stewart W. E. II, , & De Somer P. 1973; Studies on the mechanism of the priming effect of interferon on interferon production by cell cultures exposed to poly(rI). poly(rC). Infection and Immunity 8:309–316
   [Google Scholar]
6. De Clercq E., Torrence P. F., Witkop B. 1974; Interferon induction by synthetic polynucleotides: importance of purine N-7 and strandwise rearrangement. Proceedings of the National Academy of Sciences of the United States of America 71:182–186
   [Google Scholar]
7. Horak I., Jungwirth C., Bodo G. 1971; Poxvirus specific cytopathic effect in interferon-treated L cells. Virology 45:456–462
   [Google Scholar]
8. Joklik W. K., Merigan T. C. 1966; Concerning the mechanism of action of interferon. Proceedings of the National Academy of Sciences of the United States of America 56:558–565
   [Google Scholar]
9. Kerr L. M., Brown R. E., Ball L. A. 1974; Increased sensitivity of cell-free protein synthesis to doublestranded RNA after interferon treatment. Nature, London 250:57–59
   [Google Scholar]
10. Margolis S. A., Oie H., Levy H. B. 1972; The effect of interferon, interferon inducers or interferon induced virus resistance on subsequent interferon production. Journal of General Virology 15:119–128
    [Google Scholar]
11. Rosztoczy L. 1971; Interferon induction by polyinosinic-polycytidylic acid in interferon pretreated L cells in absence of DEAE-dextran. Acta Virologica 15:431
    [Google Scholar]
12. Rosztoczy I., Mecs I. 1970; Enhancement of interferon synthesis by polyinosinic-polycytidylic acid in L cells pretreated with interferon. Acta Virologica 14:398–400
    [Google Scholar]
13. Stewart W. E. II, , & De Clercq E. 1974; Relationship of cytotoxicity and interferon-inducing activity of polyriboinosinic acid-polyribocytidylic acid to the molecular weights of the homopolymers. Journal of General Virology 23:83–89
    [Google Scholar]
14. Stewart W. E. II, De Clercq E., Billiau A., Desmyter J., De Somer P. 1972b; Increased susceptibility of cells treated with interferon to the toxicity of polyriboinosinic. polyribocytidylic acid. Proceedings of the National Academy of Sciences of the United States of America 69:1851–1854
    [Google Scholar]
15. Stewart W. E. II, De Clercq E., De Somer P. 1973a; Specificity of interferon-induced enhancement of toxicity for double-stranded ribonucleic acids. Journal of General Virology 18:237–246
    [Google Scholar]
16. Stewart W. E. II, De Clercq E., De Somer P. 1973b; Cellular alteration by interferon: a virus-free system for assaying interferon. Journal of Virology 10:896–901
    [Google Scholar]
17. Stewart W. E. II, De Clercq De Somer P., Berg K., Ogburn C. A., Paucker K. 1973c; Antiviral and non-antiviral activity of highly purified interferon. Nature New Biology 246:141–143
    [Google Scholar]
18. Stewart W. E. II, Gosser L. B., Lockart R. Z. Jun. 1971a; Priming : a non-antiviral function of interferon. Journal of Virology 7:792–801
    [Google Scholar]
19. Stewart W. E. II, Gosser L. B., Lockart R. Z. Jun. 1971b; Distinguishing characteristics of the interferon responses of primary and continuous mouse cell cultures. Journal of General Virology 13:35–50
    [Google Scholar]
20. Stewart W. E. II, Gosser L. B., Lockart R. Z. Jun. 1972a; The effect of priming with interferon production by two lines of L cells. Journal of General Virology 15:85–87
    [Google Scholar]
21. Taylor-Papadimitriou J., Kaixos J. 1973; Induction of interferon by ‘ Sepharose ’-bound poly(I). poly(C). Nature New Biology 245:143–144
    [Google Scholar]